Cellosaurus cell line AKI (CVCL

Cellosaurus AKI (CVCL_8170)

Cross-references
Cell line name	AKI
Accession	CVCL_8170
Resource Identification Initiative	To cite this cell line use: AKI (RRID:CVCL_8170)
Comments	Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=16643607; PubMed=20143388). Originally thought to originate from a 42 year old male patient with a melanoma. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00172. Population: African American. Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease	Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0030 (HeLa)
Sex of cell	Female
Age at sampling	30Y6M
Category	Cancer cell line
Web pages	Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications	PubMed=3145150 A. Ishii, M. Matsui, Yoshitake Terano, Yoshiaki Miura; Establishment and characterization of a novel human malignant melanoma cell line AKI. Cell. Mol. Biol. 34:255-264(1988) PubMed=16643607; DOI=10.1111/j.1749-0774.2005.00007.x Kaori Yoshino, Emi Iimura, Kaoru Saijo, Satsuki Iwase, Kiyoko Fukami, Tadao Ohno, Yuichi Obata, Yukio Nakamura; Essential role for gene profiling analysis in the authentication of human cell lines. Hum. Cell 19:43-48(2006) PubMed=20143388; DOI=10.1002/ijc.25242 Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney; Check your cultures! A list of cross-contaminated or misidentified cell lines. Int. J. Cancer 127:1-8(2010)
Cell line collections (Providers)	RCB; RCB0408 - Discontinued
Biological sample resources	BioSample; SAMN03151663
Encyclopedic resources	Wikidata; Q54749095
Polymorphism and mutation databases	IARC_TP53; 21172
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Apr-2025
Version number	24