Cellosaurus logo
expasy logo

Cellosaurus AA-2 (CVCL_8168)

[Text][XML][JSON]
Cell line name AA-2
Synonyms AA2
Accession CVCL_8168
Resource Identification Initiative To cite this cell line use: AA-2 (RRID:CVCL_8168)
Comments Population: Caucasian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Spleen; UBERON=UBERON_0002106.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11272; SPTA1; Simple; p.Ser1163Ala (c.3487T>G); ClinVar=VCV000258929; Zygosity=Homozygous (from parent cell line).
Disease Hereditary spherocytosis (NCIt: C97074)
Hereditary spherocytosis (ORDO: Orphanet_822)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6544 (WIL2)
Sex of cell Male
Age at sampling 5Y
Category Transformed cell line
Publications

PubMed=3261775; DOI=10.1084/jem.168.2.605; PMCID=PMC2188999
Sara Chaffee, Janet M. Leeds, Thomas J. Matthews, Kent James Weinhold, Michael A. Skinner, Dani Paul Bolognesi, Michael Steven Hershfield;
Phenotypic variation in the response to the human immunodeficiency virus among derivatives of the CEM T and WIL-2 B cell lines.
J. Exp. Med. 168:605-621(1988)

Cross-references
Cell line collections (Providers) BEI_Resources; ARP-135
Encyclopedic resources Wikidata; Q54607564
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number19