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Cellosaurus L3.5 (CVCL_8145)

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Cell line name L3.5
Accession CVCL_8145
Resource Identification Initiative To cite this cell line use: L3.5 (RRID:CVCL_8145)
Comments Population: African American.
Derived from site: Metastatic; Celiac axis lymph node; UBERON=UBERON_0002508.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (from parent cell line).
Disease Pancreatic adenosquamous carcinoma (NCIt: C5721)
Squamous cell carcinoma of pancreas (ORDO: Orphanet_424039)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_8146 (L3.4)
Sex of cell Female
Age at sampling 77Y
Category Cancer cell line
Publications

PubMed=1544114; DOI=10.1002/1097-0142(19920415)69:8<2060::AID-CNCR2820690810>3.0.CO;2-E
Michael P. Vezeridis, George N. Tzanakakis, Patricia A. Meitner, Craig M. Doremus, Lance M. Tibbetts, Paul Calabresi;
In vivo selection of a highly metastatic cell line from a human pancreatic carcinoma in the nude mouse.
Cancer 69:2060-2063(1992)

PubMed=15235133; DOI=10.1385/IJGC:34:1:27
George N. Tzanakakis, Andrew N. Margioris, Aristidis Michael Tsatsakis, Michael P. Vezeridis;
The metastatic potential of human pancreatic cell lines in the liver of nude mice correlates well with cathepsin B activity.
Int. J. Gastrointest. Cancer 34:27-38(2003)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8145
Encyclopedic resources Wikidata; Q54901022
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number19