Cellosaurus cell line HN-8 (CVCL

Cellosaurus HN-8 (CVCL_8131)

Cross-references
Cell line name	HN-8
Synonyms	HN8; LICR-LON-HN8
Accession	CVCL_8131
Resource Identification Initiative	To cite this cell line use: HN-8 (RRID:CVCL_8131)
Comments	Doubling time: 170 hours (PubMed=7195729). Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
Sequence variations	Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=2183872).
Disease	Laryngeal squamous cell carcinoma (NCIt: C4044) Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	56Y
Category	Cancer cell line
Publications	PubMed=7195729; DOI=10.1038/bjc.1981.115; PMCID=PMC2010719 Dorothy M. Easty, Gerald C. Easty, Richard Lawrance Carter, Paul Monaghan, Leslie J. Butler; Ten human carcinoma cell lines derived from squamous carcinomas of the head and neck. Br. J. Cancer 43:772-785(1981) PubMed=2183872; DOI=10.1038/bjc.1990.80; PMCID=PMC1971288 Gill Rumsby, Richard Lawrance Carter, Barry Austin Gusterson; Low incidence of ras oncogene activation in human squamous cell carcinomas. Br. J. Cancer 61:365-368(1990) DOI=10.1016/B978-0-12-333530-2.50007-1 Thomas E. Carey; Head and neck tumor cell lines. (In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.79-120; Academic Press; New York; USA (1994)
Cell line databases/resources	cancercelllines; CVCL_8131
Encyclopedic resources	Wikidata; Q54889997
Polymorphism and mutation databases	Cosmic; 706655
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	19