Cellosaurus cell line H-69 (CVCL

Cross-references
Cell line name	H-69
Synonyms	H69
Accession	CVCL_8121
Resource Identification Initiative	To cite this cell line use: H-69 (RRID:CVCL_8121)
Comments	Doubling time: 118 hours (PubMed=8023938). Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Liver; UBERON=UBERON_0002107. Cell type: Cholangiocyte; CL=CL_1000488.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Adult
Category	Transformed cell line
Publications	PubMed=8023938; DOI=10.1152/ajpgi.1994.266.6.G1060 Shelley A. Grubman, Ronald D. Perrone, Des W. Lee, Sandra L. Murray, Linda C. Rogers, Leslie Ian Wolkoff, Andrew E. Mulberg, Van Cherington, Douglas M. Jefferson; Regulation of intracellular pH by immortalized human intrahepatic biliary epithelial cell lines. Am. J. Physiol. 266:G1060-G1070(1994) PubMed=10094943; DOI=10.1002/hep.510290423 Jongwon Park, Gregory James Gores, Tushar Patel; Lipopolysaccharide induces cholangiocyte proliferation via an interleukin-6-mediated activation of p44/p42 mitogen-activated protein kinase. Hepatology 29:1037-1043(1999)
Cell line databases/resources	Lonza; 712
Encyclopedic resources	Wikidata; Q54872199
Entry history
Entry creation	04-Apr-2012
Last entry update	14-Aug-2025
Version number	10