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Cellosaurus H2K mdx (CVCL_8120)

[Text version]
Cell line name H2K mdx
Synonyms H2K-mdx; H2K/mdx
Accession CVCL_8120
Resource Identification Initiative To cite this cell line use: H2K mdx (RRID:CVCL_8120)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Limb, muscle; UBERON=UBERON_0003661.
Cell type: Myoblast; CL=CL_0000056.
Sequence variations
  • Mutation; MGI; MGI:94909; Dmd; Simple; p.Gln995Ter (c.2983C>T); Zygosity=Hemizygous; Note=mdx mutation (from inference of mdx mice mutation).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: (CBA/Ca x C57BL/10)Tg(H2Kb-tsA58) Immortomouse x mdx.
Sex of cell Male
Age at sampling 1-2D
Category Conditionally immortalized cell line
Publications

PubMed=8150209; DOI=10.1006/dbio.1994.1103
Jennifer E. Morgan, Jonathan R. Beauchamp, Charles N. Pagel, Michelle Peckham, Paris Ataliotis, Parmjit S. Jat, Mark David Noble, Karen Farmer, Terence A. Partridge;
Myogenic cell lines derived from transgenic mice carrying a thermolabile T antigen: a model system for the derivation of tissue-specific and mutation-specific cell lines.
Dev. Biol. 162:486-498(1994)

Cross-references
Cell line databases/resources Lonza; 1505
Encyclopedic resources Wikidata; Q54872046
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number14