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Cellosaurus HMy.2 B (CVCL_8119)

[Text version]
Cell line name HMy.2 B
Synonyms LICR-Lon-HMy-2; LICR-LON-HMy2; LICR.LON.HMy2; Licr.Lon.Hmy2; LICRLON/My2; Hmy2; LICR-2
Accession CVCL_8119
Resource Identification Initiative To cite this cell line use: HMy.2 B (RRID:CVCL_8119)
Comments Group: Hybridoma fusion partner cell line.
Population: Caucasian.
Doubling time: 24 hours (Patent=US4695538).
Selected for resistance to: ChEBI; CHEBI_63486; 8-azaguanine.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
HLA typing Source: IPD-IMGT/HLA=10744
Class I
HLA-AA*02:01
HLA-BB*35:03
HLA-CC*04:01

Source: CLS=302008
Class I
HLA-AA*02:01:01,03:01:01
HLA-BB*15:01:01,35:03:01
HLA-CC*03:04:01,04:01:01
Class II
HLA-DPDPB1*03:01:01,04:01:01
HLA-DQDQA1*03:01:01,05:05:01
DQB1*03:01:01,03:02:01
HLA-DRDRB1*04:01:01,12:01:01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1072 (ARH-77)
Children:
CVCL_DD92 (Ge1)CVCL_F825 (HMy2.A3m)CVCL_3714 (HMy2.C1R)
CVCL_DD90 (Hu44)
Sex of cell Female
Age at sampling 33Y
Category Transformed cell line
STR profile Source(s): CLS=302008; TKG=TKG 0221

Markers:
AmelogeninX
CSF1PO6,10
D2S133817
D3S135816
D5S81810,13
D7S8207,12
D8S117914,15
D13S31711,13
D16S5399,13 (TKG=TKG 0221)
13 (CLS=302008)
D18S514,16
D19S43314,15
D21S1129,30
FGA20,21
TH018,9.3
TPOX8
vWA17

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Publications

PubMed=7140810; DOI=10.1002/eji.1830120804
Paul A.W. Edwards, Carissa M. Smith, Alexander Munro Neville, Michael J. O'Hare;
A human-hybridoma system based on a fast-growing mutant of the ARH-77 plasma cell leukemia-derived line.
Eur. J. Immunol. 12:641-648(1982)

PubMed=6350451; DOI=10.4049/jimmunol.131.3.1201
Paul G. Abrams, James A. Knost, Gregory Clarke, Shannon Wilburn, Robert K. Oldham, Kenneth Alan Foon;
Determination of the optimal human cell lines for development of human hybridomas.
J. Immunol. 131:1201-1204(1983)

PubMed=6864164; DOI=10.1084/jem.158.1.53; PMCID=PMC2187084
Alan N. Houghton, Hannah Brooks, Richard J. Cote, Michael C. Taormina, Herbert Friedrich Oettgen, Lloyd John Old;
Detection of cell surface and intracellular antigens by human monoclonal antibodies. Hybrid cell lines derived from lymphocytes of patients with malignant melanoma.
J. Exp. Med. 158:53-65(1983)

DOI=10.1007/978-1-4613-2823-0_29
Abraham Karpas;
Viruses and human leukemia in vitro.
(In book chapter) Human leukemia. Cytochemical and ultrastructural techniques in diagnosis and research. Developments in Oncology, Vol. 14; Polliack, Aaron (eds.); pp.495-526; Martinus Nijhoff Publishing; Boston; USA (1984)

PubMed=6582512; DOI=10.1073/pnas.81.2.568; PMCID=PMC344720
Michael Jules Mattes, Carlos Cordon-Cardo, John L. Lewis Jr., Lloyd John Old, Kenneth Oliver Lloyd;
Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies.
Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984)

Patent=US4695538
Richard J. Cote, Timothy M. Thomson, Alan N. Houghton, Herbert Friedrich Oettgen, Lloyd John Old, Carlos C. Cardo;
Human monoclonal antibodies to cell surface antigens.
Patent number US4695538, 22-Sep-1987

Cross-references
Cell line collections (Providers) CLS; 302008
TKG; TKG 0221
Cell line databases/resources IPD-IMGT/HLA; 10744
Encyclopedic resources Wikidata; Q54889980
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number23