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Cellosaurus HMy.2 B (CVCL_8119)

[Text version]
Cell line name HMy.2 B
Synonyms LICR-Lon-HMy-2; LICR-LON-HMy2; LICR.LON.HMy2; Licr.Lon.Hmy2; LICRLON/My2; Hmy2; LICR-2
Accession CVCL_8119
Resource Identification Initiative To cite this cell line use: HMy.2 B (RRID:CVCL_8119)
Comments Group: Hybridoma fusion partner cell line.
Population: Caucasian.
Doubling time: 24 hours (Patent=US4695538).
Selected for resistance to: ChEBI; CHEBI:63486; 8-azaguanine.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
HLA typing Source: IPD-IMGT/HLA=10744
Class I
HLA-AA*02:01
HLA-BB*35:03
HLA-CC*04:01

Source: CLS=302008
Class I
HLA-AA*02:01:01,03:01:01
HLA-BB*15:01:01,35:03:01
HLA-CC*03:04:01,04:01:01
Class II
HLA-DPDPB1*03:01:01,04:01:01
HLA-DQDQA1*03:01:01,05:05:01
DQB1*03:01:01,03:02:01
HLA-DRDRB1*04:01:01,12:01:01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1072 (ARH-77)
Children:
CVCL_DD92 (Ge1)CVCL_F825 (HMy2.A3m)CVCL_3714 (HMy2.C1R)
CVCL_DD90 (Hu44)
Sex of cell Female
Age at sampling 33Y
Category Transformed cell line
STR profile Source(s): CLS=302008; TKG=TKG 0221

Markers:
AmelogeninX
CSF1PO6,10
D2S133817
D3S135816
D5S81810,13
D7S8207,12
D8S117914,15
D13S31711,13
D16S5399,13 (TKG=TKG 0221)
13 (CLS=302008)
D18S514,16
D19S43314,15
D21S1129,30
FGA20,21
TH018,9.3
TPOX8
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=7140810; DOI=10.1002/eji.1830120804
Edwards P.A.W., Smith C.M., Neville A.M., O'Hare M.J.
A human-hybridoma system based on a fast-growing mutant of the ARH-77 plasma cell leukemia-derived line.
Eur. J. Immunol. 12:641-648(1982)

PubMed=6350451; DOI=10.4049/jimmunol.131.3.1201
Abrams P.G., Knost J.A., Clarke G., Wilburn S., Oldham R.K., Foon K.A.
Determination of the optimal human cell lines for development of human hybridomas.
J. Immunol. 131:1201-1204(1983)

PubMed=6864164; DOI=10.1084/jem.158.1.53
Houghton A.N., Brooks H., Cote R.J., Taormina M.C., Oettgen H.F., Old L.J.
Detection of cell surface and intracellular antigens by human monoclonal antibodies. Hybrid cell lines derived from lymphocytes of patients with malignant melanoma.
J. Exp. Med. 158:53-65(1983)

DOI=10.1007/978-1-4613-2823-0_29
Karpas A.
Viruses and human leukemia in vitro.
(In) Human leukemia. Cytochemical and ultrastructural techniques in diagnosis and research. Developments in Oncology, Vol. 14; Polliack A. (eds.); pp.495-526; Martinus Nijhoff Publishing; Boston (1984)

PubMed=6582512; DOI=10.1073/pnas.81.2.568
Mattes M.J., Cordon-Cardo C., Lewis J.L. Jr., Old L.J., Lloyd K.O.
Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies.
Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984)

Patent=US4695538
Cote R.J., Thomson T.M., Houghton A.N., Oettgen H.F., Old L.J., Cardo C.C.
Human monoclonal antibodies to cell surface antigens.
Patent number US4695538, 22-Sep-1987

Cross-references
Cell line collections (Providers) CLS; 302008
TKG; TKG 0221
Cell line databases/resources IPD-IMGT/HLA; 10744
Encyclopedic resources Wikidata; Q54889980
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number22