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Cellosaurus FL-318 (CVCL_8095)

[Text version]
Cell line name FL-318
Synonyms FL318
Accession CVCL_8095
Resource Identification Initiative To cite this cell line use: FL-318 (RRID:CVCL_8095)
Comments Population: Japanese.
Doubling time: 45.2 hours (PubMed=8847894).
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; miRNA profiling; Microarray.
Omics: Variations; Array-based CGH.
Omics: Variations; CNV analysis.
Misspelling: AKA96-9; IARC_TP53=6005; Note=Not really a misspelling but an assignment of a name based on first author of publication and date because assignment of correct cell line name was not done correctly.
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Sequence variations
Disease Follicular lymphoma (NCIt: C3209)
Follicular lymphoma (ORDO: Orphanet_545)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line
Publications

PubMed=2180570
Ryuichi Amakawa, Shiro Fukuhara, Hitoshi Ohno, Satoru Tanabe, Mitsuru Horii, Fumio Matsuyama, Isoroku Kato, Tokio Kakita, Osamu Nagauchi;
Amplified and rearranged bcl-2 gene in two lymphoma cell lines, FL-218 and FL-318, carrying a 14;18 translocation.
Cancer Res. 50:2423-2428(1990)

PubMed=8847894
Akiyoshi Tani, Eiji Tatsumi, Fumihiko Nakamura, Shunichi Kumagai, Yoshiyuki Kosaka, Kimihiko Sano, Hajime Nakamura, Ryuichi Amakawa, Hitoshi Ohno;
Sensitivity to dexamethasone and absence of bcl-2 protein in Burkitt's lymphoma cell line (Black93) derived from a patient with acute tumor lysis syndrome: comparative study with other BL and non-BL lines.
Leukemia 10:1592-1603(1996)

PubMed=8878455; DOI=10.1111/j.1349-7006.1996.tb02122.x; PMCID=PMC5921203
Takashi Akasaka, Mikiko Muramatsu, Norimitsu Kadowaki, Hitoshi Ohno, Kanji Ishizaki, Hirohiko Yamabe, Shiro Fukuhara, Minoru Okuma;
p53 mutation in B-cell lymphoid neoplasms with reference to oncogene rearrangements associated with chromosomal translocations.
Jpn. J. Cancer Res. 87:930-937(1996)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=12967475; DOI=10.1111/j.1349-7006.2003.tb01518.x; PMCID=PMC11160262
Yoshitomo Maesako, Takashi Uchiyama, Hitoshi Ohno;
Comparison of gene expression profiles of lymphoma cell lines from transformed follicular lymphoma, Burkitt's lymphoma and de novo diffuse large B-cell lymphoma.
Cancer Sci. 94:774-781(2003)

PubMed=14990977; DOI=10.1038/sj.leu.2403323
Mardiah Suci Hardianti, Eiji Tatsumi, Meilani Syampurnawati, Kiyoshi Furuta, Katsuyasu Saigo, Yuji Nakamachi, Shunichi Kumagai, Hitoshi Ohno, Satoru Tanabe, M. Uchida, Norimasa Yasuda;
Activation-induced cytidine deaminase expression in follicular lymphoma: association between AID expression and ongoing mutation in FL.
Leukemia 18:826-831(2004)

PubMed=19278952; DOI=10.1182/blood-2009-01-202028; PMCID=PMC3401058
Cheng Li, Sang-Woo Kim, Deepak Rai, Aswani R. Bolla, Siddharth Adhvaryu, Marsha C. Kinney, Ryan S. Robetorye, Ricardo C.T. Aguiar;
Copy number abnormalities, MYC activity, and the genetic fingerprint of normal B cells mechanistically define the microRNA profile of diffuse large B-cell lymphoma.
Blood 113:6681-6690(2009)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8095
Anatomy/cell type resources BTO; BTO_0002520
Encyclopedic resources Wikidata; Q54834955
Gene expression databases GEO; GSM380126
Polymorphism and mutation databases IARC_TP53; 6005
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number20