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Cellosaurus SK-MEL-197 (CVCL_8082)

[Text version]
Cell line name SK-MEL-197
Synonyms SK-Mel-197; SK-MEL 197; SK-Mel 197; SKMEL-197; SKMEL197
Accession CVCL_8082
Resource Identification Initiative To cite this cell line use: SK-MEL-197 (RRID:CVCL_8082)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=24576830).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=21343389; DOI=10.1158/0008-5472.CAN-10-2958
Rose A.E., Poliseno L., Wang J.-H., Clark M., Pearlman A., Wang G.-M., Vega y Saenz de Miera E.C., Medicherla R., Christos P.J., Shapiro R., Pavlick A., Darvishian F., Zavadil J., Polsky D., Hernando E., Ostrer H., Osman I.
Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression.
Cancer Res. 71:2561-2571(2011)

PubMed=24576830; DOI=10.1158/0008-5472.CAN-13-2625
Nissan M.H., Pratilas C.A., Jones A.M., Ramirez R., Won H., Liu C.-L., Tiwari S., Kong L., Hanrahan A.J., Yao Z., Merghoub T., Ribas A., Chapman P.B., Yaeger R., Taylor B.S., Schultz N., Berger M.F., Rosen N., Solit D.B.
Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence.
Cancer Res. 74:2340-2350(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8082
Lonza; 1342
Encyclopedic resources Wikidata; Q54953901
Gene expression databases GEO; GSM555132
GEO; GSM555185
Polymorphism and mutation databases Cosmic; 685212
Cosmic; 1122263
Progenetix; CVCL_8082
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number19