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Cellosaurus 397-mel (CVCL_8050)

[Text version]
Cell line name 397-mel
Synonyms 397-MEL; 397-Mel; 397 mel; 397mel; 397
Accession CVCL_8050
Resource Identification Initiative To cite this cell line use: 397-mel (RRID:CVCL_8050)
Comments From: Rosenberg, Steven A.; Surgery Branch, National Cancer Institute, National Institutes of Health; Bethesda; USA.
Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
Sequence variations
HLA typing Source: PubMed=9670966
Class I
HLA-AA*01,25
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A1DW (397-mel/A31)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=8027550; DOI=10.4049/jimmunol.153.3.1225
Francesco M. Marincola, Peter Shamamian, Richard B. Alexander, James R. Gnarra, Regina L. Turetskaya, Sergei Arturovich Nedospasov, Toni B. Simonis, Jeffery Karl Taubenberger, John R. Yannelli, Arnold Mixon, Nicholas P. Restifo ...Show all 13 authors... , Meenhard Herlyn, Steven A. Rosenberg; Show fewer authors
Loss of HLA haplotype and B locus down-regulation in melanoma cell lines.
J. Immunol. 153:1225-1237(1994)

PubMed=8081556; DOI=10.1097/00002371-199407000-00002; PMCID=PMC2561308
Francesco M. Marincola, Peter Shamamian, Toni B. Simonis, Andrea D. Abati, Julia A. Hackett, Teresita O'Dea, Patricia A. Fetsch, John R. Yannelli, Nicholas P. Restifo, James J. Mule, Steven A. Rosenberg;
Locus-specific analysis of human leukocyte antigen class I expression in melanoma cell lines.
J. Immunother. Emphasis Tumor Immunol. 16:13-23(1994)

PubMed=8537970; DOI=10.1093/jnci/88.2.100; PMCID=PMC2248456
Nicholas P. Restifo, Francesco M. Marincola, Yutaka Kawakami, Jeffery Karl Taubenberger, John R. Yannelli, Steven A. Rosenberg;
Loss of functional beta 2-microglobulin in metastatic melanomas from five patients receiving immunotherapy.
J. Natl. Cancer Inst. 88:100-108(1996)

PubMed=9670966; DOI=10.4049/jimmunol.161.2.877
Maria P. Bettinotti, Christina J. Kim, Kang-Hun Lee, Matthew Roden, Janice N. Cormier, Monica C. Panelli, Kenneth K. Parker, Francesco M. Marincola;
Stringent allele/epitope requirements for MART-1/Melan A immunodominance: implications for peptide-based immunotherapy.
J. Immunol. 161:877-889(1998)

PubMed=9759882; DOI=10.4049/jimmunol.161.7.3596
Rong-Fu Wang, Samuel L. Johnston, Gang Zeng, Suzanne Louise Topalian, Douglas J. Schwartzentruber, Steven A. Rosenberg;
A breast and melanoma-shared tumor antigen: T cell responses to antigenic peptides translated from different open reading frames.
J. Immunol. 161:3596-3606(1998)

PubMed=10048982; DOI=10.1002/(SICI)1097-0215(19990301)80:5<781::AID-IJC24>3.0.CO;2-A; PMCID=PMC2072935
Janice N. Cormier, Monica C. Panelli, Julia A. Hackett, Maria P. Bettinotti, Arnold Mixon, John R. Wunderlich, Linda L. Parker, Nicholas P. Restifo, Soldano Ferrone, Francesco M. Marincola;
Natural variation of the expression of HLA and endogenous antigen modulates CTL recognition in an in vitro melanoma model.
Int. J. Cancer 80:781-790(1999)

PubMed=10754339; DOI=10.4049/jimmunol.164.8.4382
Monica C. Panelli, Maria P. Bettinotti, Kate Lally, Galen Anthony Ohnmacht, Yong Li, Paul F. Robbins, Adam Riker, Steven A. Rosenberg, Francesco M. Marincola;
A tumor-infiltrating lymphocyte from a melanoma metastasis with decreased expression of melanoma differentiation antigens recognizes MAGE-12.
J. Immunol. 164:4382-4392(2000)

PubMed=11121133; DOI=10.1046/j.1523-1747.2000.00199.x
Pedro M. Lacal, Cristina M. Failla, Elena Pagani, Teresa Odorisio, Cataldo Schietroma, Sabrina Falcinelli, Giovanna Zambruno, Stefania D'Atri;
Human melanoma cells secrete and respond to placenta growth factor and vascular endothelial growth factor.
J. Invest. Dermatol. 115:1000-1007(2000)

PubMed=15467732; DOI=10.1038/sj.onc.1208152
Hideaki Tanami, Issei Imoto, Akira Hirasawa, Yasuhiro Yuki, Itaru Sonoda, Jun Inoue, Kohichiroh Yasui, Akiko Misawa-Furihata, Yutaka Kawakami, Johji Inazawa;
Involvement of overexpressed wild-type BRAF in the growth of malignant melanoma cell lines.
Oncogene 23:8796-8804(2004)

PubMed=19799798; DOI=10.1186/1471-2407-9-352; PMCID=PMC2763007
Milena Casula, Antonio Muggiano, Antonio Cossu, Mario Budroni, Corrado Caraco, Paolo Antonio Ascierto, Elena Pagani, Ignazio Stanganelli, Sergio Canzanella, Maria Cristina Sini, Grazia Palomba, Giuseppe Palmieri;
Italian Melanoma Intergroup (IMI)
Role of key-regulator genes in melanoma susceptibility and pathogenesis among patients from South Italy.
BMC Cancer 9:352.1-352.11(2009)

PubMed=21424129; DOI=10.3892/or.2011.1220
Antonella Manca, Maria Cristina Sini, Francesco Izzo, Paolo Antonio Ascierto, Fabiana Tatangelo, Gerardo Botti, Giusy Gentilcore, Marilena Capone, Nicola Mozzillo, Carla Rozzo, Antonio Cossu ...Show all 13 authors... , Francesco Tanda, Giuseppe Palmieri; Show fewer authors
Induction of arginosuccinate synthetase (ASS) expression affects the antiproliferative activity of arginine deiminase (ADI) in melanoma cells.
Oncol. Rep. 25:1495-1502(2011)

PubMed=29492214; DOI=10.18632/oncotarget.23989; PMCID=PMC5823576
Maria Cristina Sini, Valentina Doneddu, Panagiotis Paliogiannis, Milena Casula, Maria Colombino, Antonella Manca, Gerardo Botti, Paolo Antonio Ascierto, Amelia Lissia, Antonio Cossu, Giuseppe Palmieri;
Genetic alterations in main candidate genes during melanoma progression.
Oncotarget 9:8531-8541(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8050
CGH-DB; 9295-4
Encyclopedic resources Wikidata; Q54585254
Polymorphism and mutation databases Cosmic; 876699
Cosmic; 897736
Cosmic; 905209
Cosmic; 1295344
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number24