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Cellosaurus 1102-mel (CVCL_8030)

[Text version]
Cell line name 1102-mel
Synonyms 1102-MEL; 1102 mel; 1102mel; 1102; Mel-1102; MEL1102
Accession CVCL_8030
Resource Identification Initiative To cite this cell line use: 1102-mel (RRID:CVCL_8030)
Comments From: Rosenberg S.A.; Surgery Branch, National Cancer Institute, National Institutes of Health; Bethesda; USA.
Omics: Array-based CGH.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Not specified.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (PubMed=15467732).
HLA typing Source: PubMed=15592718
Class I
HLA-AA*02:01,24:02
HLA-BB*15:01:01:01,55:01
HLA-CC*03:02
Class II
HLA-DPDPB1*04:02,06:01
HLA-DQDQB1*06:02,03:01:01
HLA-DRDRB1*15:01,04:01
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-046

Markers:
AmelogeninX
CSF1PO10,11
D3S135816,18
D7S82010
D13S3179,13
FGA22,23.2
TH019,9.3
TPOX9,11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=8027550; DOI=10.4049/jimmunol.153.3.1225
Marincola F.M., Shamamian P., Alexander R.B., Gnarra J.R., Turetskaya R.L., Nedospasov S.A., Simonis T.B., Taubenberger J.K., Yannelli J.R., Mixon A., Restifo N.P., Herlyn M., Rosenberg S.A.
Loss of HLA haplotype and B locus down-regulation in melanoma cell lines.
J. Immunol. 153:1225-1237(1994)

PubMed=8081556; DOI=10.1097/00002371-199407000-00002
Marincola F.M., Shamamian P., Simonis T.B., Abati A.D., Hackett J.A., O'Dea T., Fetsch P.A., Yannelli J.R., Restifo N.P., Mule J.J., Rosenberg S.A.
Locus-specific analysis of human leukocyte antigen class I expression in melanoma cell lines.
J. Immunother. Emphasis Tumor Immunol. 16:13-23(1994)

PubMed=10048982; DOI=10.1002/(SICI)1097-0215(19990301)80:5<781::AID-IJC24>3.0.CO;2-A
Cormier J.N., Panelli M.C., Hackett J.A., Bettinotti M.P., Mixon A., Wunderlich J.R., Parker L.L., Restifo N.P., Ferrone S., Marincola F.M.
Natural variation of the expression of HLA and endogenous antigen modulates CTL recognition in an in vitro melanoma model.
Int. J. Cancer 80:781-790(1999)

PubMed=10754339; DOI=10.4049/jimmunol.164.8.4382
Panelli M.C., Bettinotti M.P., Lally K., Ohnmacht G.A., Li Y., Robbins P.F., Riker A., Rosenberg S.A., Marincola F.M.
A tumor-infiltrating lymphocyte from a melanoma metastasis with decreased expression of melanoma differentiation antigens recognizes MAGE-12.
J. Immunol. 164:4382-4392(2000)

PubMed=15467732; DOI=10.1038/sj.onc.1208152
Tanami H., Imoto I., Hirasawa A., Yuki Y., Sonoda I., Inoue J., Yasui K., Misawa-Furihata A., Kawakami Y., Inazawa J.
Involvement of overexpressed wild-type BRAF in the growth of malignant melanoma cell lines.
Oncogene 23:8796-8804(2004)

PubMed=15592718; DOI=10.1007/s00262-004-0561-5
Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello Osuna F., Dodi I.A., Lopez-Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G., Garrido F.
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

PubMed=18172304; DOI=10.1158/0008-5472.CAN-07-1939
Sabatino M., Zhao Y.-D., Voiculescu S., Monaco A., Robbins P.F., Karai L., Nickoloff B.J., Maio M., Selleri S., Marincola F.M., Wang E.
Conservation of genetic alterations in recurrent melanoma supports the melanoma stem cell hypothesis.
Cancer Res. 68:122-131(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8030
CGH-DB; 9293-4
ESTDAB; ESTDAB-046
Anatomy/cell type resources BTO; BTO:0002947
Encyclopedic resources Wikidata; Q54554922
Gene expression databases GEO; GSM218054
Polymorphism and mutation databases Cosmic; 905207
Cosmic; 972280
Progenetix; CVCL_8030
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number21