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Cellosaurus CW12 (CVCL_7952)

[Text version]
Cell line name CW12
Synonyms CW12-1E
Accession CVCL_7952
Resource Identification Initiative To cite this cell line use: CW12 (RRID:CVCL_7952)
Sequence variations
  • Gene fusion; HGNC; 3819; FOXO1 + HGNC; 8617; PAX3; Name(s)=PAX3-FOXO1, PAX3-FKHR (PubMed=7536457; PubMed=8275086).
Disease Alveolar rhabdomyosarcoma (NCIt: C3749)
Alveolar rhabdomyosarcoma (ORDO: Orphanet_99756)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=1680555
Malik R., Gope M., Womer R.B., Nagashunmugam T., Margolin J.F., Basu A., Scher C.D.
Structure and expression of the beta-platelet-derived growth factor receptor gene in human tumor cell lines.
Cancer Res. 51:5626-5631(1991)

PubMed=8275086; DOI=10.1038/ng1193-230
Galili N., Davis R.J., Fredericks W.J., Mukhopadhyay S., Rauscher F.J. III, Emanuel B.S., Rovera G., Barr F.G.
Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma.
Nat. Genet. 5:230-235(1993)

PubMed=7536457; DOI=10.1002/gcc.2870120305
Biegel J.A., Nycum L.M., Valentine V.A., Barr F.G., Shapiro D.N.
Detection of the t(2;13)(q35;q14) and PAX3-FKHR fusion in alveolar rhabdomyosarcoma by fluorescence in situ hybridization.
Genes Chromosomes Cancer 12:186-192(1995)

PubMed=23665679; DOI=10.1038/onc.2013.129
Sokolowski E., Turina C.B., Kikuchi K., Langenau D.M., Keller C.
Proof-of-concept rare cancers in drug development: the case for rhabdomyosarcoma.
Oncogene 33:1877-1889(2014)

Cross-references
Encyclopedic resources Wikidata; Q54815089
Polymorphism and mutation databases Cosmic; 1097742
Cosmic; 1104555
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number11