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Cellosaurus MOLM-7 (CVCL_7917)

[Text version]
Cell line name MOLM-7
Synonyms MOLM7
Accession CVCL_7917
Resource Identification Initiative To cite this cell line use: MOLM-7 (RRID:CVCL_7917)
Comments Population: Japanese.
Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2122 ! MOLM-6
CVCL_7918 ! MOLM-8
CVCL_7919 ! MOLM-9
CVCL_7920 ! MOLM-10
CVCL_7921 ! MOLM-11
CVCL_L075 ! MOLM-12
Sex of cell Male
Age at sampling 44Y
Category Cancer cell line
Publications

PubMed=7873501
Kazue Tsuji-Takayama, Takashi Kamiya, Shuji Nakamura, Yoshinobu Matsuo, Tomiro Adachi, Teruhiko Tsubota, Jiro Imanishi, Jun Minowada;
Establishment of multiple leukemia cell lines with diverse myeloid and/or megakaryoblastoid characteristics from a single Ph1 positive chronic myelogenous leukemia blood sample.
Hum. Cell 7:167-171(1994)

PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4
Kaoru Inoue, Takashi Kohno, Satoshi Takakura, Yasuhide Hayashi, Hideaki Mizoguchi, Jun Yokota;
Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines.
Leuk. Res. 24:255-262(2000)

PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1
Kaoru Inoue, Takashi Kohno, Satoshi Takakura, Yasuhide Hayashi, Hideaki Mizoguchi, Jun Yokota;
Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000), 255-262.
Leuk. Res. 25:275-278(2001)

PubMed=11734303; DOI=10.1016/S0145-2126(01)00097-2
Martina Hradcova, Iuri Marinov, Jiri T. Novak, Jitka Nemcova, Petr Stockbauer;
Monoclonal antibody to human chronic myeloid leukemia cell line MOLM-7 specifically reacts with an antigen of apoptotic cells.
Leuk. Res. 26:45-54(2002)

PubMed=14504097; DOI=10.1182/blood-2003-02-0418
Takeshi Taketani, Tomohiko Taki, Kanji Sugita, Yoshiyuki Furuichi, Eiichi Ishii, Ryoji Hanada, Masahiro Tsuchida, Kenichi Sugita, Kohmei Ida, Yasuhide Hayashi;
FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy.
Blood 103:1085-1088(2004)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Hilmar Quentmeier, Roderick A.F. MacLeod, Margarete Zaborski, Hans Gunther Drexler;
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=23955599; DOI=10.1038/ng.2731
Ayana Kon, Lee-Yung Shih, Masashi Minamino, Masashi Sanada, Yuichi Shiraishi, Yasunobu Nagata, Ken-ichi Yoshida, Yusuke Okuno, Masashige Bando, Ryuichiro Nakato, Shumpei Ishikawa ...Show all 41 authors... , Aiko Sato-Otsubo, Genta Nagae, Aiko Nishimoto, Claudia Haferlach, Daniel Nowak, Yusuke Sato, Tamara Alpermann, Masao Nagasaki, Teppei Shimamura, Hiroko Tanaka, Kenichi Chiba, Ryo Yamamoto, Tomoyuki Yamaguchi, Makoto Otsu, Naoshi Obara, Mamiko Sakata-Yanagimoto, Tsuyoshi Nakamaki, Ken Ishiyama, Florian Nolte, Wolf-Karsten Hofmann, Shuichi Miyawaki, Shigeru Chiba, Hiraku Mori, Hiromitsu Nakauchi, Harold Phillip Koeffler, Hiroyuki Aburatani, Torsten Haferlach, Katsuhiko Shirahige, Satoru Miyano, Seishi Ogawa; Show fewer authors
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
Nat. Genet. 45:1232-1237(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7917
Encyclopedic resources Wikidata; Q54906330
Polymorphism and mutation databases Cosmic; 996325
Cosmic; 998757
Cosmic; 999770
Cosmic; 1012094
Cosmic; 1037677
Cosmic; 2089676
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number19