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Cellosaurus MOLM-14 (CVCL_7916)

[Text version]
Cell line name MOLM-14
Synonyms Molm-14; Molm 14; Molm14; MOLM14
Accession CVCL_7916
Resource Identification Initiative To cite this cell line use: MOLM-14 (RRID:CVCL_7916)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: 3-4 days (PubMed=9305600); ~50 hours (DSMZ=ACC-777).
Omics: Genomics; ChIP-seq; H3K79me1.
Omics: Proteomics; PTM; Phosphorylation; Quantitative.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2119 ! MOLM-13
Sex of cell Male
Age at sampling 20Y
Category Cancer cell line
STR profile Source(s): COG; DepMap=ACH-001574; DSMZ=ACC-777; JCRB=JCRB1812

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133823,25
D3S135815
D5S81810,11
D7S82010,12
D8S117913,14
D13S31710,11
D16S53910,11
D18S5113,15
D19S43312,14
D21S1130,31
FGA21,23
Penta D9,12
Penta E18,19
TH017
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=9305600; DOI=10.1038/sj.leu.2400768
Yoshinobu Matsuo, Roderick A.F. MacLeod, Cord C. Uphoff, Hans Gunther Drexler, Chiharu Nishizaki, Yoshio Katayama, Genki Kimura, Nobuharu Fujii, Eijiro Omoto, Mine Harada, Kunzo Orita;
Two acute monocytic leukemia (AML-M5a) cell lines (MOLM-13 and MOLM-14) with interclonal phenotypic heterogeneity showing MLL-AF9 fusion resulting from an occult chromosome insertion, ins(11;9)(q23;p22p23).
Leukemia 11:1469-1477(1997)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=12529668; DOI=10.1038/sj.leu.2402740
Hilmar Quentmeier, Julia Reinhardt, Margarete Zaborski, Hans Gunther Drexler;
FLT3 mutations in acute myeloid leukemia cell lines.
Leukemia 17:120-124(2003)

PubMed=21552520; DOI=10.1371/journal.pone.0019169; PMCID=PMC3084268
Ting-Lei Gu, Julie Nardone, Yi Wang, Marc Loriaux, Judit Villen, Sean A. Beausoleil, Meghan Tucker, Jon M. Kornhauser, Jian-Min Ren, Joan MacNeill, Steven P. Gygi ...Show all 15 authors... , Brian Jay Druker, Michael Charles Heinrich, John Rush, Roberto D. Polakiewicz; Show fewer authors
Survey of activated FLT3 signaling in leukemia.
PLoS ONE 6:e19169.1-e19169.10(2011)

Cross-references
Cell line collections (Providers) DSMZ; ACC-777
JCRB; JCRB1812
Cell line databases/resources Cell_Model_Passport; SIDM00436
DepMap; ACH-001574
DSMZCellDive; ACC-777
Lonza; 978
Anatomy/cell type resources BTO; BTO_0005720
Chemistry resources ChEMBL-Cells; CHEMBL3706571
ChEMBL-Targets; CHEMBL3706570
PubChem_Cell_line; CVCL_7916
Encyclopedic resources Wikidata; Q54906323
Experimental variables resources EFO; EFO_0022446
Gene expression databases GEO; GSM2037134
GEO; GSM2037135
GEO; GSM3145574
GEO; GSM3145724
Polymorphism and mutation databases Cosmic; 787418
Cosmic; 1150898
Cosmic; 1281333
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number29