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Cellosaurus UT-SCC-7 (CVCL_7868)

[Text version]
Cell line name UT-SCC-7
Synonyms UT-SCC7; University of Turku-Squamous Cell Carcinoma-7
Accession CVCL_7868
Resource Identification Initiative To cite this cell line use: UT-SCC-7 (RRID:CVCL_7868)
Comments Derived from site: Metastatic; Temple, skin; UBERON=UBERON_8480028.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Gly266Glu (c.797G>A); ClinVar=VCV000161516; Zygosity=Unspecified (PubMed=8782485).
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line
Publications

PubMed=8782485; DOI=10.1046/j.1365-2184.1996.01009.x
Servomaa K., Kiuru A., Grenman R., Pekkola-Heino K., Pulkkinen J.O., Rytomaa T.
p53 mutations associated with increased sensitivity to ionizing radiation in human head and neck cancer cell lines.
Cell Prolif. 29:219-230(1996)

PubMed=9187133
Soukka T., Salmi M., Joensuu H., Hakkinen L., Sointu P., Koulu L., Kalimo K., Klemi P., Grenman R., Jalkanen S.T.
Regulation of CD44v6-containing isoforms during proliferation of normal and malignant epithelial cells.
Cancer Res. 57:2281-2289(1997)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=22427941; DOI=10.1371/journal.pone.0033041
Toriseva M., Ala-aho R., Peltonen S., Peltonen J., Grenman R., Kahari V.-M.
Keratinocyte growth factor induces gene expression signature associated with suppression of malignant phenotype of cutaneous squamous carcinoma cells.
PLoS ONE 7:E33041-E33041(2012)

PubMed=27305645; DOI=10.1111/exd.13109
Farshchian M., Nissinen L., Grenman R., Kahari V.-M.
Dasatinib promotes apoptosis of cutaneous squamous carcinoma cells by regulating activation of ERK1/2.
Exp. Dermatol. 26:89-92(2017)

PubMed=28322200; DOI=10.1016/j.ajpath.2017.01.006
Riihila P., Nissinen L., Farshchian M., Kallajoki M., Kivisaari A., Meri S., Grenman R., Peltonen S., Peltonen J., Pihlajaniemi T., Heljasvaara R., Kahari V.-M.
Complement component C3 and complement factor B promote growth of cutaneous squamous cell carcinoma.
Am. J. Pathol. 187:1186-1197(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7868
Encyclopedic resources Wikidata; Q54992189
Polymorphism and mutation databases IARC_TP53; 11067
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number12