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Cellosaurus UT-SCC-1A (CVCL_7818)

[Text version]
Cell line name UT-SCC-1A
Synonyms University of Turku-Squamous Cell Carcinoma-1A
Accession CVCL_7818
Resource Identification Initiative To cite this cell line use: UT-SCC-1A (RRID:CVCL_7818)
Comments Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Oral cavity, gingiva; UBERON=UBERON_0001828.
Sequence variations
Disease Gingival squamous cell carcinoma (NCIt: C129857)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7819 ! UT-SCC-1B
Sex of cell Female
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): PubMed=30135316

Markers:
AmelogeninX
CSF1PO10,12
D2S133825
D3S135818
D5S81811,12
D7S8209
D8S117910,11
D13S3179,10
D16S53911
D18S5116
D19S43315
D21S1129,31
FGA22,24
TH019
TPOX8,9
vWA15,17

Run an STR similarity search on this cell line
Publications

DOI=10.1016/B978-0-12-333530-2.50007-1
Thomas E. Carey;
Head and neck tumor cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.79-120; Academic Press; New York; USA (1994)

PubMed=8725545; DOI=10.3109/00016489609137854
Kirsi Pekkola-Heino, Kristina Servomaa, Anne Kiuru, Reidar Grenman;
Increased radiosensitivity is associated with p53 mutations in cell lines derived from oral cavity carcinoma.
Acta Oto-Laryngol. 116:341-344(1996)

PubMed=8782485; DOI=10.1046/j.1365-2184.1996.01009.x
Kristina Servomaa, Anne Kiuru, Reidar Grenman, Kirsi Pekkola-Heino, Jaakko O. Pulkkinen, Tapio Rytomaa;
p53 mutations associated with increased sensitivity to ionizing radiation in human head and neck cancer cell lines.
Cell Prolif. 29:219-230(1996)

PubMed=9187133
Tero Soukka, Marko Salmi, Heikki Joensuu, Lan Hakkinen, Petri Sointu, Leena Koulu, Kirsti Kalimo, Pekka Klemi, Reidar Grenman, Sirpa T. Jalkanen;
Regulation of CD44v6-containing isoforms during proliferation of normal and malignant epithelial cells.
Cancer Res. 57:2281-2289(1997)

PubMed=17312569; DOI=10.1002/hed.20478
Charles J. Lin, Jennifer Rubin Grandis, Thomas E. Carey, Susanne M. Gollin, Theresa L. Whiteside, Wayne M. Koch, Robert Louis Ferris, Stephen Y. Lai;
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=30135316; DOI=10.1172/jci.insight.122204; PMCID=PMC6141174
Stephen M.F. Jamieson, Peter Tsai, Maria K. Kondratyev, Pratha Budhani, Arthur Liu, Neil N. Senzer, E. Gabriela Chiorean, Shadia I. Jalal, John Joseph Nemunaitis, Dennis Kee, Avik Shome ...Show all 35 authors... , Way W. Wong, Dan Li, Nooriyah Poonawala-Lohani, Purvi M. Kakadia, Nicholas S. Knowlton, Courtney R.H. Lynch, Cho R. Hong, Tet Woo Lee, Reidar Grenman, Laura Caporiccio, Trevor David McKee, Mark Zaidi, Sehrish Butt, Andrew M.J. Macann, Nicholas P. McIvor, John M. Chaplin, Kevin O. Hicks, Stefan Klaus Bohlander, Bradly G. Wouters, Charles P. Hart, Cristin Gregor Print, William R. Wilson, Michael A. Curran, Francis W. Hunter; Show fewer authors
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma.
JCI Insight 3:e122204.1-e122204.19(2018)

DOI=10.1158/1538-7445.AM2020-507
Maria K. Kondratyev, Aleksandra Pesic, Anna Dvorkin-Sheva, Troy Ketela, Jason Moffat, Marianne Koritzinsky, Bradly G. Wouters;
Repurposing of FDA approved drugs for treatment of metastatic HNSCC.
Cancer Res. 80 Suppl. 16:507-507(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7818
Encyclopedic resources Wikidata; Q54992080
Polymorphism and mutation databases IARC_TP53; 11059
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number16