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Cellosaurus UT-SCC-19B (CVCL_7817)

[Text version]
Cell line name UT-SCC-19B
Synonyms UTSCC19B; University of Turku-Squamous Cell Carcinoma-19B
Accession CVCL_7817
Resource Identification Initiative To cite this cell line use: UT-SCC-19B (RRID:CVCL_7817)
Comments Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; miRNA profiling; Microarray.
Omics: Variations; Array-based CGH.
Derived from site: In situ; Larynx, glottis; UBERON=UBERON_0002486.
Sequence variations
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7816 ! UT-SCC-19A
Sex of cell Male
Age at sampling 44Y
Category Cancer cell line
STR profile Source(s): PubMed=30135316

Markers:
AmelogeninX
CSF1PO12
D2S133819
D3S135815
D5S81810,12
D7S82012
D8S117910,14
D13S31711,13
D16S53912
D18S5116
D19S43318.2
D21S1132.2
FGA24
TH016
TPOX8
vWA14,19

Run an STR similarity search on this cell line
Publications

PubMed=8782485; DOI=10.1046/j.1365-2184.1996.01009.x
Kristina Servomaa, Anne Kiuru, Reidar Grenman, Kirsi Pekkola-Heino, Jaakko O. Pulkkinen, Tapio Rytomaa;
p53 mutations associated with increased sensitivity to ionizing radiation in human head and neck cancer cell lines.
Cell Prolif. 29:219-230(1996)

PubMed=15287027; DOI=10.1002/gcc.20066
Satoru Takebayashi, Arthur Hickson, Tetsuya Ogawa, Kwang-Yoon Jung, Hiroyuki Mineta, Yo Ueda, Reidar Grenman, Susan G. Fisher, Thomas E. Carey;
Loss of chromosome arm 18q with tumor progression in head and neck squamous cancer.
Genes Chromosomes Cancer 41:145-154(2004)

PubMed=16715129; DOI=10.1038/sj.onc.1209690
Anna-Kaarina Jarvinen, Reija Autio, Saija Haapa-Paananen, Maija Wolf, Matti Saarela, Reidar Grenman, Ilmo Leivo, Olli-Pekka Kallioniemi, Antti A. Makitie, Outi Monni;
Identification of target genes in laryngeal squamous cell carcinoma by high-resolution copy number and gene expression microarray analyses.
Oncogene 25:6997-7008(2006)

PubMed=17312569; DOI=10.1002/hed.20478
Charles J. Lin, Jennifer Rubin Grandis, Thomas E. Carey, Susanne M. Gollin, Theresa L. Whiteside, Wayne M. Koch, Robert Louis Ferris, Stephen Y. Lai;
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=26694163; DOI=10.1371/journal.pone.0144924; PMCID=PMC4692263
Joanna Janiszewska, Marcin Szaumkessel, Magdalena Kostrzewska-Poczekaj, Kinga Bednarek, Julia Paczkowska, Joanna Jackowska, Reidar Grenman, Krzysztof Szyfter, Malgorzata Wierzbicka, Maciej Giefing, Malgorzata Jarmuz-Szymczak;
Global miRNA expression profiling identifies miR-1290 as novel potential oncomiR in laryngeal carcinoma.
PLoS ONE 10:e0144924.1-e0144924.13(2015)

PubMed=30135316; DOI=10.1172/jci.insight.122204; PMCID=PMC6141174
Stephen M.F. Jamieson, Peter Tsai, Maria K. Kondratyev, Pratha Budhani, Arthur Liu, Neil N. Senzer, E. Gabriela Chiorean, Shadia I. Jalal, John Joseph Nemunaitis, Dennis Kee, Avik Shome ...Show all 35 authors... , Way W. Wong, Dan Li, Nooriyah Poonawala-Lohani, Purvi M. Kakadia, Nicholas S. Knowlton, Courtney R.H. Lynch, Cho R. Hong, Tet Woo Lee, Reidar Grenman, Laura Caporiccio, Trevor David McKee, Mark Zaidi, Sehrish Butt, Andrew M.J. Macann, Nicholas P. McIvor, John M. Chaplin, Kevin O. Hicks, Stefan Klaus Bohlander, Bradly G. Wouters, Charles P. Hart, Cristin Gregor Print, William R. Wilson, Michael A. Curran, Francis W. Hunter; Show fewer authors
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma.
JCI Insight 3:e122204.1-e122204.19(2018)

DOI=10.1158/1538-7445.AM2020-507
Maria K. Kondratyev, Aleksandra Pesic, Anna Dvorkin-Sheva, Troy Ketela, Jason Moffat, Marianne Koritzinsky, Bradly G. Wouters;
Repurposing of FDA approved drugs for treatment of metastatic HNSCC.
Cancer Res. 80 Suppl. 16:507-507(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7817
Encyclopedic resources Wikidata; Q54992078
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number18