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Cellosaurus UT-SCC-16B (CVCL_7813)

[Text version]
Cell line name UT-SCC-16B
Synonyms University of Turku-Squamous Cell Carcinoma-16B
Accession CVCL_7813
Resource Identification Initiative To cite this cell line use: UT-SCC-16B (RRID:CVCL_7813)
Comments Omics: Genomics; Whole exome sequencing.
Caution: UT-SCC-16A and UT-SCC-16B are supposed to originate from the same patient but have totally different STR profiles.
Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
Sequence variations
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7812 ! UT-SCC-16A
Sex of cell Female
Age at sampling 77Y
Category Cancer cell line
STR profile Source(s): PubMed=30135316

Markers:
AmelogeninX
CSF1PO10,11
D2S133827
D3S135814,17
D5S81812,14
D7S8209,11
D8S117912,13
D13S3179,12
D16S53911
D18S5114,15
D19S43314,15.2
D21S1131,32.2
FGA21,22
TH017.9
TPOX9
vWA18,19

Run an STR similarity search on this cell line
Publications

PubMed=8725545; DOI=10.3109/00016489609137854
Kirsi Pekkola-Heino, Kristina Servomaa, Anne Kiuru, Reidar Grenman;
Increased radiosensitivity is associated with p53 mutations in cell lines derived from oral cavity carcinoma.
Acta Oto-Laryngol. 116:341-344(1996)

PubMed=8782485; DOI=10.1046/j.1365-2184.1996.01009.x
Kristina Servomaa, Anne Kiuru, Reidar Grenman, Kirsi Pekkola-Heino, Jaakko O. Pulkkinen, Tapio Rytomaa;
p53 mutations associated with increased sensitivity to ionizing radiation in human head and neck cancer cell lines.
Cell Prolif. 29:219-230(1996)

PubMed=15287027; DOI=10.1002/gcc.20066
Satoru Takebayashi, Arthur Hickson, Tetsuya Ogawa, Kwang-Yoon Jung, Hiroyuki Mineta, Yo Ueda, Reidar Grenman, Susan G. Fisher, Thomas E. Carey;
Loss of chromosome arm 18q with tumor progression in head and neck squamous cancer.
Genes Chromosomes Cancer 41:145-154(2004)

PubMed=17312569; DOI=10.1002/hed.20478
Charles J. Lin, Jennifer Rubin Grandis, Thomas E. Carey, Susanne M. Gollin, Theresa L. Whiteside, Wayne M. Koch, Robert Louis Ferris, Stephen Y. Lai;
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=30135316; DOI=10.1172/jci.insight.122204; PMCID=PMC6141174
Stephen M.F. Jamieson, Peter Tsai, Maria K. Kondratyev, Pratha Budhani, Arthur Liu, Neil N. Senzer, E. Gabriela Chiorean, Shadia I. Jalal, John Joseph Nemunaitis, Dennis Kee, Avik Shome ...Show all 35 authors... , Way W. Wong, Dan Li, Nooriyah Poonawala-Lohani, Purvi M. Kakadia, Nicholas S. Knowlton, Courtney R.H. Lynch, Cho R. Hong, Tet Woo Lee, Reidar Grenman, Laura Caporiccio, Trevor David McKee, Mark Zaidi, Sehrish Butt, Andrew M.J. Macann, Nicholas P. McIvor, John M. Chaplin, Kevin O. Hicks, Stefan Klaus Bohlander, Bradly G. Wouters, Charles P. Hart, Cristin Gregor Print, William R. Wilson, Michael A. Curran, Francis W. Hunter; Show fewer authors
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma.
JCI Insight 3:e122204.1-e122204.19(2018)

DOI=10.1158/1538-7445.AM2020-507
Maria K. Kondratyev, Aleksandra Pesic, Anna Dvorkin-Sheva, Troy Ketela, Jason Moffat, Marianne Koritzinsky, Bradly G. Wouters;
Repurposing of FDA approved drugs for treatment of metastatic HNSCC.
Cancer Res. 80 Suppl. 16:507-507(2020)

Cross-references
Encyclopedic resources Wikidata; Q54992072
Polymorphism and mutation databases Cosmic; 1140775
Cosmic; 1219859
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number19