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Cellosaurus UM-SCC-9 (CVCL_7793)

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Cell line name UM-SCC-9
Synonyms UMSCC-9; UMSCC9; UM-SCC9; SCC9; University of Michigan-Squamous Cell Carcinoma-9
Accession CVCL_7793
Resource Identification Initiative To cite this cell line use: UM-SCC-9 (RRID:CVCL_7793)
Comments Caution: Indicated as originating from a 74 year old patient in PubMed=3855324 and from a 72 year old in PubMed=18006756.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 71Y
Category Cancer cell line
STR profile Source(s): PubMed=19760794

Markers:
AmelogeninX
D3S135814
D5S81812
D7S8208,11
D8S11799,13
D13S31711,14
D18S5113,15
D21S1130,31.2
FGA22
vWA17,18

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Publications

PubMed=3855324; DOI=10.1288/00005537-198501000-00012
Shan R. Baker;
An in vivo model for squamous cell carcinoma of the head and neck.
Laryngoscope 95:43-56(1985)

PubMed=1851275; DOI=10.1177/019459989110400304
Carol R. Bradford, Susan E. Zacks, Elliot J. Androphy, Lucie Gregoire, Wayne D. Lancaster, Thomas E. Carey;
Human papillomavirus DNA sequences in cell lines derived from head and neck squamous cell carcinomas.
Otolaryngol. Head Neck Surg. 104:303-310(1991)

DOI=10.1016/B978-0-12-333530-2.50007-1
Thomas E. Carey;
Head and neck tumor cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.79-120; Academic Press; New York; USA (1994)

PubMed=17312569; DOI=10.1002/hed.20478
Charles J. Lin, Jennifer Rubin Grandis, Thomas E. Carey, Susanne M. Gollin, Theresa L. Whiteside, Wayne M. Koch, Robert Louis Ferris, Stephen Y. Lai;
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=18006756; DOI=10.1158/1078-0432.CCR-07-1591
Jay Friedman, Liesl K. Nottingham, Praveen Duggal, Francisco G. Pernas, Bin Yan, Xin-Ping Yang, Zhong Chen, Carter Van Waes;
Deficient TP53 expression, function, and cisplatin sensitivity are restored by quinacrine in head and neck cancer.
Clin. Cancer Res. 13:6568-6578(2007)

PubMed=19760794; DOI=10.1002/hed.21198; PMCID=PMC3292176
J. Chad Brenner, Martin P. Graham, Bhavna Kumar, Lindsay M. Saunders, Robbi Ann Kupfer, Robert H. Lyons, Carol R. Bradford, Thomas E. Carey;
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.
Head Neck 32:417-426(2010)

Cross-references
Encyclopedic resources Wikidata; Q54990945
Polymorphism and mutation databases Cosmic; 1130353
Cosmic; 1317413
IARC_TP53; 25906
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number21