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Cellosaurus UM-SCC-81B (CVCL_7784)

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Cell line name UM-SCC-81B
Synonyms UMSCC-81B; UMSCC81B; University of Michigan-Squamous Cell Carcinoma-81B
Accession CVCL_7784
Resource Identification Initiative To cite this cell line use: UM-SCC-81B (RRID:CVCL_7784)
Comments Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Omics: Variations; CNV analysis.
Derived from site: In situ; Oral cavity, tonsil, tonsillar pillar; UBERON=UBERON_0036274.
Sequence variations
Disease Tonsillar squamous cell carcinoma (NCIt: C8183)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7783 ! UM-SCC-81A
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): PubMed=19760794

Markers:
AmelogeninX,Y
D3S135817
D5S81811,12
D7S8209,11
D8S117910,13
D13S3179,11
D18S5114
D21S1129
FGA20,22
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=9041179
Christopher J. Frank, Kenneth Donald McClatchey, Kenneth O. Devaney, Thomas E. Carey;
Evidence that loss of chromosome 18q is associated with tumor progression.
Cancer Res. 57:824-827(1997)

PubMed=12884349; DOI=10.1002/hed.10274
Carol R. Bradford, Shao-Bo Zhu, Haruko Ogawa, Tetsuya Ogawa, Matthew Ubell, Ajita Narayan, Garfield Johnson, Gregory T. Wolf, Susan G. Fisher, Thomas E. Carey;
p53 mutation correlates with cisplatin sensitivity in head and neck squamous cell carcinoma lines.
Head Neck 25:654-661(2003)

PubMed=15287027; DOI=10.1002/gcc.20066
Satoru Takebayashi, Arthur Hickson, Tetsuya Ogawa, Kwang-Yoon Jung, Hiroyuki Mineta, Yo Ueda, Reidar Grenman, Susan G. Fisher, Thomas E. Carey;
Loss of chromosome arm 18q with tumor progression in head and neck squamous cancer.
Genes Chromosomes Cancer 41:145-154(2004)

PubMed=16785414; DOI=10.1001/archotol.132.6.668
Maria J. Worsham, Kang Mei Chen, Venkata Meduri, Anders O.H. Nygren, Abdellatif Errami, Jan P. Schouten, Michael S. Benninger;
Epigenetic events of disease progression in head and neck squamous cell carcinoma.
Arch. Otolaryngol. Head Neck Surg. 132:668-677(2006)

PubMed=17312569; DOI=10.1002/hed.20478
Charles J. Lin, Jennifer Rubin Grandis, Thomas E. Carey, Susanne M. Gollin, Theresa L. Whiteside, Wayne M. Koch, Robert Louis Ferris, Stephen Y. Lai;
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=19760794; DOI=10.1002/hed.21198; PMCID=PMC3292176
J. Chad Brenner, Martin P. Graham, Bhavna Kumar, Lindsay M. Saunders, Robbi Ann Kupfer, Robert H. Lyons, Carol R. Bradford, Thomas E. Carey;
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.
Head Neck 32:417-426(2010)

PubMed=31090975; DOI=10.1002/hed.25803; PMCID=PMC6692232
Jacqueline E. Mann, Aditi Kulkarni, Andrew C. Birkeland, Judy Kafelghazal, Julia Eisenberg, Brittany M. Jewell, Megan L. Ludwig, Matthew Edward Spector, Hui Jiang, Thomas E. Carey, J. Chad Brenner;
The molecular landscape of the University of Michigan laryngeal squamous cell carcinoma cell line panel.
Head Neck 41:3114-3124(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7784
Encyclopedic resources Wikidata; Q54990931
Gene expression databases GEO; GSM3631285
Polymorphism and mutation databases IARC_TP53; 18886
Progenetix; CVCL_7784
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number22