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Cellosaurus UM-SCC-74B (CVCL_7780)

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Cell line name UM-SCC-74B
Synonyms UMSCC-74B; UMSCC74B; University of Michigan-Squamous Cell Carcinoma-74B
Accession CVCL_7780
Resource Identification Initiative To cite this cell line use: UM-SCC-74B (RRID:CVCL_7780)
Sequence variations
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7779 ! UM-SCC-74A
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
STR profile Source(s): PubMed=19760794

Markers:
AmelogeninX
D3S135815,16
D5S81812
D7S82011
D8S117912,13
D13S31712
D18S5117
D21S1130,34.2
FGA21,26
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=12884349; DOI=10.1002/hed.10274
Carol R. Bradford, Shao-Bo Zhu, Haruko Ogawa, Tetsuya Ogawa, Matthew Ubell, Ajita Narayan, Garfield Johnson, Gregory T. Wolf, Susan G. Fisher, Thomas E. Carey;
p53 mutation correlates with cisplatin sensitivity in head and neck squamous cell carcinoma lines.
Head Neck 25:654-661(2003)

PubMed=15287027; DOI=10.1002/gcc.20066
Satoru Takebayashi, Arthur Hickson, Tetsuya Ogawa, Kwang-Yoon Jung, Hiroyuki Mineta, Yo Ueda, Reidar Grenman, Susan G. Fisher, Thomas E. Carey;
Loss of chromosome arm 18q with tumor progression in head and neck squamous cancer.
Genes Chromosomes Cancer 41:145-154(2004)

PubMed=17312569; DOI=10.1002/hed.20478
Charles J. Lin, Jennifer Rubin Grandis, Thomas E. Carey, Susanne M. Gollin, Theresa L. Whiteside, Wayne M. Koch, Robert Louis Ferris, Stephen Y. Lai;
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=19760794; DOI=10.1002/hed.21198; PMCID=PMC3292176
J. Chad Brenner, Martin P. Graham, Bhavna Kumar, Lindsay M. Saunders, Robbi Ann Kupfer, Robert H. Lyons, Carol R. Bradford, Thomas E. Carey;
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.
Head Neck 32:417-426(2010)

Cross-references
Encyclopedic resources Wikidata; Q54990913
Polymorphism and mutation databases IARC_TP53; 21108
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17