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Cellosaurus UM-SCC-57 (CVCL_7770)

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Cell line name UM-SCC-57
Synonyms UMSCC-57; UMSCC57; University of Michigan-Squamous Cell Carcinoma-57
Accession CVCL_7770
Resource Identification Initiative To cite this cell line use: UM-SCC-57 (RRID:CVCL_7770)
Comments Omics: Genomics; Whole exome sequencing.
Omics: Variations; CNV analysis.
Sequence variations
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): PubMed=19760794

Markers:
AmelogeninX,Y
D3S135815
D5S81811,12
D7S8209,10
D8S117912
D13S3179,12
D18S5117,18
D21S1129
FGA23,24
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=12884349; DOI=10.1002/hed.10274
Carol R. Bradford, Shao-Bo Zhu, Haruko Ogawa, Tetsuya Ogawa, Matthew Ubell, Ajita Narayan, Garfield Johnson, Gregory T. Wolf, Susan G. Fisher, Thomas E. Carey;
p53 mutation correlates with cisplatin sensitivity in head and neck squamous cell carcinoma lines.
Head Neck 25:654-661(2003)

PubMed=17312569; DOI=10.1002/hed.20478
Charles J. Lin, Jennifer Rubin Grandis, Thomas E. Carey, Susanne M. Gollin, Theresa L. Whiteside, Wayne M. Koch, Robert Louis Ferris, Stephen Y. Lai;
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=19760794; DOI=10.1002/hed.21198; PMCID=PMC3292176
J. Chad Brenner, Martin P. Graham, Bhavna Kumar, Lindsay M. Saunders, Robbi Ann Kupfer, Robert H. Lyons, Carol R. Bradford, Thomas E. Carey;
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.
Head Neck 32:417-426(2010)

PubMed=31090975; DOI=10.1002/hed.25803; PMCID=PMC6692232
Jacqueline E. Mann, Aditi Kulkarni, Andrew C. Birkeland, Judy Kafelghazal, Julia Eisenberg, Brittany M. Jewell, Megan L. Ludwig, Matthew Edward Spector, Hui Jiang, Thomas E. Carey, J. Chad Brenner;
The molecular landscape of the University of Michigan laryngeal squamous cell carcinoma cell line panel.
Head Neck 41:3114-3124(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7770
Encyclopedic resources Wikidata; Q54990890
Gene expression databases GEO; GSM3631281
Polymorphism and mutation databases IARC_TP53; 18884
Progenetix; CVCL_7770
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number19