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Cellosaurus UM-SCC-35 (CVCL_7746)

[Text version]
Cell line name UM-SCC-35
Synonyms UMSCC-35; UMSCC35; University of Michigan-Squamous Cell Carcinoma-35
Accession CVCL_7746
Resource Identification Initiative To cite this cell line use: UM-SCC-35 (RRID:CVCL_7746)
Comments Doubling time: 38 +- 2 hours (PubMed=9139877).
Omics: Genomics; Whole genome sequencing; Low read coverage.
Sequence variations
Disease Tonsillar squamous cell carcinoma (NCIt: C8183)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
STR profile Source(s): PubMed=19760794

Markers:
AmelogeninX,Y
D3S135817
D5S81813
D7S8209,11
D8S117911,15,16
D13S31711
D18S5115
D21S1136
FGA18.2,26
vWA15,18

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Publications

DOI=10.1016/B978-0-12-333530-2.50007-1
Thomas E. Carey;
Head and neck tumor cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.79-120; Academic Press; New York; USA (1994)

PubMed=9139877; DOI=10.1002/(SICI)1097-0215(19970502)71:3<410::AID-IJC18>3.0.CO;2-J
Marij J.P. Welters, Anne Marie Josephine Fichtinger-Schepman, Robert A. Baan, Mario A.J.A. Hermsen, Wim J.F. van der Vijgh, Jacqueline Cloos, Boudewijn J.M. Braakhuis;
Relationship between the parameters cellular differentiation, doubling time and platinum accumulation and cisplatin sensitivity in a panel of head and neck cancer cell lines.
Int. J. Cancer 71:410-415(1997)

PubMed=17312569; DOI=10.1002/hed.20478
Charles J. Lin, Jennifer Rubin Grandis, Thomas E. Carey, Susanne M. Gollin, Theresa L. Whiteside, Wayne M. Koch, Robert Louis Ferris, Stephen Y. Lai;
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=19760794; DOI=10.1002/hed.21198; PMCID=PMC3292176
J. Chad Brenner, Martin P. Graham, Bhavna Kumar, Lindsay M. Saunders, Robbi Kupfer, Robert H. Lyons, Carol R. Bradford, Thomas E. Carey;
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.
Head Neck 32:417-426(2010)

PubMed=26122845; DOI=10.1158/0008-5472.CAN-15-0528
Chantal Stoepker, Najim Ameziane, Petra van der Lelij, Irsan E. Kooi, Anneke B. Oostra, Martin A. Rooimans, Saskia E. van Mil, Arjen Brink, Ralf Dietrich, Jesper A. Balk, Bauke Ylstra ...Show all 14 authors... , Hans Joenje, Stephan M. Feller, Ruud H. Brakenhoff; Show fewer authors
Defects in the Fanconi anemia pathway and chromatid cohesion in head and neck cancer.
Cancer Res. 75:3543-3553(2015)

PubMed=31541927; DOI=10.1016/j.oraloncology.2019.09.004; PMCID=PMC7372097
Anne M. van Harten, Jos B. Poell, Marijke Buijze, Arjen Brink, Susanne I. Wells, C. Rene Leemans, Rob M.F. Wolthuis, Ruud H. Brakenhoff;
Characterization of a head and neck cancer-derived cell line panel confirms the distinct TP53-proficient copy number-silent subclass.
Oral Oncol. 98:53-61(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7746
Encyclopedic resources Wikidata; Q54990855
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number21