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Cellosaurus UM-SCC-27 (CVCL_7737)

[Text version]
Cell line name UM-SCC-27
Synonyms UMSCC-27; UMSCC27; University of Michigan-Squamous Cell Carcinoma-27
Accession CVCL_7737
Resource Identification Initiative To cite this cell line use: UM-SCC-27 (RRID:CVCL_7737)
Comments Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): PubMed=19760794

Markers:
AmelogeninX,Y
D3S135814
D5S81812,13
D7S8208,11
D8S117912,13
D13S3178
D18S5114,16
D21S1129,32.2
FGA19
vWA17,18

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Publications

PubMed=16035614; DOI=10.1007/s10585-004-6918-5
Robert Mandic, Thomas Ludwig, Hans Oberleithner, Jochen Alfred Werner;
Evaluation of head and neck squamous cell carcinoma invasiveness by the electrical resistance breakdown assay.
Clin. Exp. Metastasis 21:699-704(2004)

PubMed=16203773; DOI=10.1158/1078-0432.CCR-05-0378
Robert Mandic, Chantal J. Schamberger, Julia F. Muller, Matthias Geyer, Li Zhu, Thomas E. Carey, Reidar Grenman, Anja A. Dunne, Jochen Alfred Werner;
Reduced cisplatin sensitivity of head and neck squamous cell carcinoma cell lines correlates with mutations affecting the COOH-terminal nuclear localization signal of p53.
Clin. Cancer Res. 11:6845-6852(2005)

PubMed=17312569; DOI=10.1002/hed.20478
Charles J. Lin, Jennifer Rubin Grandis, Thomas E. Carey, Susanne M. Gollin, Theresa L. Whiteside, Wayne M. Koch, Robert Louis Ferris, Stephen Y. Lai;
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=19760794; DOI=10.1002/hed.21198; PMCID=PMC3292176
J. Chad Brenner, Martin P. Graham, Bhavna Kumar, Lindsay M. Saunders, Robbi Kupfer, Robert H. Lyons, Carol R. Bradford, Thomas E. Carey;
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.
Head Neck 32:417-426(2010)

Cross-references
Encyclopedic resources Wikidata; Q54990843
Polymorphism and mutation databases Cosmic; 1483460
IARC_TP53; 21638
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17