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Cellosaurus UM-SCC-20 (CVCL_7729)

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Cell line name UM-SCC-20
Synonyms UMSCC-20; UMSCC20; University of Michigan-Squamous Cell Carcinoma-20
Accession CVCL_7729
Resource Identification Initiative To cite this cell line use: UM-SCC-20 (RRID:CVCL_7729)
Comments Derived from site: Metastatic; Neck; UBERON=UBERON_0000974.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro71_Pro72del (c.211_216del6); Zygosity=Unspecified (PubMed=12884349).
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line
STR profile Source(s): PubMed=19760794

Markers:
AmelogeninX,Y
D3S135814,15
D5S81811,12
D7S8209,10
D8S117912,15
D13S3178,10
D18S5113,15
D21S1128,30.2
FGA18,22.2
vWA16,18

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Publications

DOI=10.1016/B978-0-12-333530-2.50007-1
Thomas E. Carey;
Head and neck tumor cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.79-120; Academic Press; New York; USA (1994)

PubMed=12884349; DOI=10.1002/hed.10274
Carol R. Bradford, Shao-Bo Zhu, Haruko Ogawa, Tetsuya Ogawa, Matthew Ubell, Ajita Narayan, Garfield Johnson, Gregory T. Wolf, Susan G. Fisher, Thomas E. Carey;
p53 mutation correlates with cisplatin sensitivity in head and neck squamous cell carcinoma lines.
Head Neck 25:654-661(2003)

PubMed=17312569; DOI=10.1002/hed.20478
Charles J. Lin, Jennifer Rubin Grandis, Thomas E. Carey, Susanne M. Gollin, Theresa L. Whiteside, Wayne M. Koch, Robert Louis Ferris, Stephen Y. Lai;
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=19760794; DOI=10.1002/hed.21198; PMCID=PMC3292176
J. Chad Brenner, Martin P. Graham, Bhavna Kumar, Lindsay M. Saunders, Robbi Ann Kupfer, Robert H. Lyons, Carol R. Bradford, Thomas E. Carey;
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.
Head Neck 32:417-426(2010)

Cross-references
Encyclopedic resources Wikidata; Q54990834
Polymorphism and mutation databases IARC_TP53; 18880
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number18