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Cellosaurus GD25 (CVCL_7264)

[Text version]
Cell line name GD25
Accession CVCL_7264
Resource Identification Initiative To cite this cell line use: GD25 (RRID:CVCL_7264)
Comments Knockout cell: Method=Gene trap; MGI; MGI:96610; Itgb1.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: 129S2/SvPas.
Hierarchy Parent: CVCL_E078 (G-201)
Children:
CVCL_GR75 (GD25T)
Sex of cell Male
Age at sampling Blastocyst stage
Category Transformed cell line
Web pages Info; -; -; https://web.archive.org/web/20160325165513/http://bioinfoweb.com/CLDB-GD25.htm
Publications

PubMed=7533171; DOI=10.1083/jcb.128.5.979; PMCID=PMC2120384
Reinhard Fassler, Martin Pfaff, John Murphy, Angelika Anna Noegel, Staffan Johansson, Rupert Timpl, Richard Albrecht;
Lack of beta 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocysts.
J. Cell Biol. 128:979-988(1995)

PubMed=8567726; DOI=10.1083/jcb.132.1.227; PMCID=PMC2120698
Krister Wennerberg, Lars Lohikangas, Elon Donald Gullberg, Martin Pfaff, Staffan Johansson, Reinhard Fassler;
Beta 1 integrin-dependent and -independent polymerization of fibronectin.
J. Cell Biol. 132:227-238(1996)

PubMed=10574722; DOI=10.1242/jcs.112.24.4751
Gunbjorg Svineng, Staffan Johansson;
Integrin subunits (beta)1C-1 and (beta)1C-2 expressed in GD25T cells are retained and degraded intracellularly rather than localised to the cell surface.
J. Cell Sci. 112:4751-4761(1999)

PubMed=10601344; DOI=10.1083/jcb.147.6.1325; PMCID=PMC2168093
Clotilde Gimond, Arjan van der Flier, Sanne van Delft, Cord Brakebusch, Ingrid Kuikman, John G. Collard, Reinhard Fassler, Arnoud Sonnenberg;
Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function.
J. Cell Biol. 147:1325-1340(1999)

Cross-references
Encyclopedic resources Wikidata; Q54835527
Experimental variables resources EFO; EFO_0022803
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number14