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Cellosaurus DEV [Human lymphoma] (CVCL_7187)

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Cell line name DEV [Human lymphoma]
Accession CVCL_7187
Resource Identification Initiative To cite this cell line use: DEV [Human lymphoma] (RRID:CVCL_7187)
Comments Problematic cell line: Misclassified. Originally thought to be a Hodgkin lymphoma cell line, but seems to be from a nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL).
Doubling time: ~3 days (PubMed=3881158).
Omics: Variations; SNP array analysis.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Disease Nodular lymphocyte predominant Hodgkin lymphoma (NCIt: C7258)
Nodular lymphocyte predominant Hodgkin lymphoma (ORDO: Orphanet_86893)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Publications

PubMed=3881158; DOI=10.1002/1097-0142(19850215)55:4<683::AID-CNCR2820550402>3.0.CO;2-O
Sibrandes Poppema, Bauke de Jong, Jane E. Atmosoerodjo-Briggs, Vera Idenburg, Lydia Visser, Lou F.M.H. de Leij;
Morphologic, immunologic, enzymehistochemical and chromosomal analysis of a cell line derived from Hodgkin's disease. Evidence for a B-cell origin of Sternberg-Reed cells.
Cancer 55:683-690(1985)

PubMed=2690233; DOI=10.1007/978-3-642-83781-4_5
Michael Schaadt, Heinz Burrichter, Michael Pfreundschuh, Elizabeth Schell-Frederick, Hans Tesch, Christa Fonatsch, Harald Stein, Volker Diehl;
Biology of Hodgkin cell lines.
Recent Results Cancer Res. 117:53-61(1989)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=12581897; DOI=10.1016/S0165-4608(02)00656-8
Mattias Berglund, Emma Flordal, Jacob Gullander, Weng-Onn Lui, Catharina Larsson, Svetlana Lagercrantz, Gunilla Enblad;
Molecular cytogenetic characterization of four commonly used cell lines derived from Hodgkin lymphoma.
Cancer Genet. Cytogenet. 141:43-48(2003)

PubMed=19648161; DOI=10.3324/haematol.2009.010157; PMCID=PMC2805741
Martin A. Schumacher, Roland Schmitz, Verena Brune, Enrico Tiacci, Claudia Doring, Martin-Leo Hansmann, Reiner Siebert, Ralf Kuppers;
Mutations in the genes coding for the NF-kappaB regulating factors IkappaBalpha and A20 are uncommon in nodular lymphocyte-predominant Hodgkin's lymphoma.
Haematologica 95:153-157(2010)

PubMed=27998726; DOI=10.1016/j.ajpath.2016.10.007
Jonathan R. Fromm, Anju Thomas, Brent L. Wood;
Characterization and purification of neoplastic cells of nodular lymphocyte predominant Hodgkin lymphoma from lymph nodes by flow cytometry and flow cytometric cell sorting.
Am. J. Pathol. 187:304-317(2017)

PubMed=29533902; DOI=10.1515/hsz-2017-0321
Hans Gunther Drexler, Claudia Pommerenke, Sonja Eberth, Stefan Nagel;
Hodgkin lymphoma cell lines: to separate the wheat from the chaff.
Biol. Chem. 399:511-523(2018)

Cross-references
Cell line databases/resources Lonza; 268
Encyclopedic resources Wikidata; Q54831018
Gene expression databases GEO; GSM1897960
Polymorphism and mutation databases Cosmic; 1293254
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number18