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Cellosaurus SCMC-L10 (CVCL_7126)

[Text version]
Cell line name SCMC-L10
Synonyms L10; Saitama Children's Medical Center-Leukemia 10
Accession CVCL_7126
Resource Identification Initiative To cite this cell line use: SCMC-L10 (RRID:CVCL_7126)
Comments Population: Japanese.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.627_632AAACAC>CCCACACGCA; Zygosity=Unspecified (PubMed=7727782).
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Children
Category Cancer cell line
Publications

CLPUB00111
Yasuhide Hayashi, Machiko Kawamura, Shigetoshi Kobayashi, Kouichi Moriwaki, Miyuki Kobayashi, Fumio Bessho, Ryoji Hanada, Keiko Yamamoto, Taijiro Mori, Shinpei Nakazawa, Akihiro Yanaginuma ...Show all 13 authors... , Yoshio Honma, Motoo Hozumi; Show fewer authors
Establishment and characterization of cell lines derived from childhood leukemias.
Int. J. Hematol. 57 Suppl. 1:124-124(1993)

PubMed=8139288; DOI=10.1016/0145-2126(94)90118-x
Seitetsu Sato, Yoshio Honma, Motoo Hozumi, Yasuhide Hayashi, Yoshinobu Matsuo, Kiyoshi Shibata, Satoshi Omura, Ken-ichiro Hino, Shigeru Tomoyasu, Nobuyoshi Tsuruoka;
Effects of herbimycin A and its derivatives on growth and differentiation of Ph1-positive acute lymphoid leukemia cell lines.
Leuk. Res. 18:221-228(1994)

PubMed=7727782; DOI=10.1182/blood.V85.9.2546.bloodjournal8592546
Machiko Kawamura, Akira Kikuchi, Shigetoshi Kobayashi, Ryoji Hanada, Keiko Yamamoto, Keizou Horibe, Takaaki Shikano, Kazuhiro Ueda, Kenshi Hayashi, Takao Sekiya, Yasuhide Hayashi;
Mutations of the p53 and ras genes in childhood t(1;19)-acute lymphoblastic leukemia.
Blood 85:2546-2552(1995)

PubMed=10233379; DOI=10.1111/j.1365-2141.1999.01284.x
F. Xu, Tomohiko Taki, Hong-Wei Yang, Ryoji Hanada, Teruaki Hongo, Hiroaki Ohnishi, Miyuki Kobayashi, Fumio Bessho, Masayoshi Yanagisawa, Yasuhide Hayashi;
Tandem duplication of the FLT3 gene is found in acute lymphoblastic leukaemia as well as acute myeloid leukaemia but not in myelodysplastic syndrome or juvenile chronic myelogenous leukaemia in children.
Br. J. Haematol. 105:155-162(1999)

PubMed=14504097; DOI=10.1182/blood-2003-02-0418
Takeshi Taketani, Tomohiko Taki, Kanji Sugita, Yoshiyuki Furuichi, Eiichi Ishii, Ryoji Hanada, Masahiro Tsuchida, Kenichi Sugita, Kohmei Ida, Yasuhide Hayashi;
FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy.
Blood 103:1085-1088(2004)

PubMed=29786757; DOI=10.1007/s12185-018-2474-7
Chihiro Tomoyasu, Toshihiko Imamura, Toshihiro Tomii, Mio Yano, Daisuke Asai, Hiroaki Goto, Akira Shimada, Masashi Sanada, Shotaro Iwamoto, Junko Takita, Masayoshi Minegishi ...Show all 14 authors... , Takeshi Inukai, Kanji Sugita, Hajime Hosoi; Show fewer authors
Copy number abnormality of acute lymphoblastic leukemia cell lines based on their genetic subtypes.
Int. J. Hematol. 108:312-318(2018)

Cross-references
Anatomy/cell type resources BTO; BTO_0004949
Encyclopedic resources Wikidata; Q54952453
Polymorphism and mutation databases Cosmic; 710460
Cosmic; 996294
Cosmic; 998689
Cosmic; 1037740
IARC_TP53; 3950
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17