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Cellosaurus NPC/HK1 (CVCL_7084)

[Text version]
Cell line name NPC/HK1
Synonyms HK1; HK-1
Accession CVCL_7084
Resource Identification Initiative To cite this cell line use: NPC/HK1 (RRID:CVCL_7084)
Comments Population: Chinese.
Virology: EBV-negative.
Doubling time: 28 +- 2 hours (PubMed=6259064).
Karyotypic information: Near triploid (PubMed=39905741).
Derived from site: In situ; Pharynx, nasopharynx; UBERON=UBERON_0001728.
Disease Nasopharyngeal carcinoma (NCIt: C3871)
Nasopharyngeal carcinoma (ORDO: Orphanet_150)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): PubMed=18196576; PubMed=39905741

Markers:
AmelogeninX
CSF1PO11,12
D2S133820,23
D3S135815
D5S81811,13
D7S8208,11
D8S117911,13
D13S31711
D16S5399,11
D18S5117
D19S43314
D21S1128,29
FGA26
Penta D9,12
Penta E15,18.4
TH017,9
TPOX8,11
vWA18,19

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Publications

PubMed=6259064; DOI=10.1002/ijc.2910260202
Huang Poon D.W.-S., Ho J.H.-C., Poon Y.-F., Chew E.-C., Saw D., Lui M., Li C.L., Mak L.S., Lai S.H., Lau W.H.
Establishment of a cell line (NPC/HK1) from a differentiated squamous carcinoma of the nasopharynx.
Int. J. Cancer 26:127-132(1980)

PubMed=12645650; DOI=10.1016/S0165-4608(02)00657-X
Wong N., Hui A.B.-Y., Fan B.-L., Lo K.-W., Pang E., Leung S.-F., Huang Poon D.W.-S., Johnson P.J.
Molecular cytogenetic characterization of nasopharyngeal carcinoma cell lines and xenografts by comparative genomic hybridization and spectral karyotyping.
Cancer Genet. Cytogenet. 140:124-132(2003)

PubMed=18196576; DOI=10.1002/ijc.23374
Chan S.Y.-Y., Choy K.-W., Tsao S.-W., Tao Q., Tang T., Chung G.T.-Y., Lo K.-W.
Authentication of nasopharyngeal carcinoma tumor lines.
Int. J. Cancer 122:2169-2171(2008)

PubMed=39905741; DOI=10.1002/cam4.70422; PMCID=PMC11794828
Makowska A., Kontny H.U., van Helden J., Hildebrandt B., Schuler H.M., Weiskirchen R.
Genetic characterization of the immortalized human nasopharyngeal carcinoma cell line NPC/HK1.
Cancer Med. 14:e70422.1-e70422.8(2025)

Cross-references
Cell line collections (Providers) Ubigene; YC-C095
Cell line databases/resources Cell_Model_Passport; SIDM01997
Anatomy/cell type resources BTO; BTO_0004899
Encyclopedic resources Wikidata; Q54930981
Experimental variables resources EFO; EFO_0022551
Polymorphism and mutation databases Cosmic; 755503
Cosmic; 923772
Cosmic; 1017618
Cosmic; 1300997
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number20