Cellosaurus cell line KP-MRT-NS (CVCL

Cellosaurus KP-MRT-NS (CVCL_7050)

Cross-references
Cell line name	KP-MRT-NS
Synonyms	Kyoto Pediatrics-Malignant Rhabdoid Tumor-NS
Accession	CVCL_7050
Resource Identification Initiative	To cite this cell line use: KP-MRT-NS (RRID:CVCL_7050)
Comments	Population: Japanese. Doubling time: 72 hours (PubMed=10417765). Karyotypic information: 46,XX,add(10)(q26) [17]; 46,XX,add(10)(q26),dic(1;2)(p22;q31) [3] (PubMed=10417765). Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Disease	Rhabdoid tumor of the kidney (NCIt: C8715) Rhabdoid tumor (ORDO: Orphanet_69077)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	11M
Category	Cancer cell line
Publications	PubMed=9920784; DOI=10.1006/bbrc.1998.9968 Toshiki Mori, Yoji Fukuda, Hiroshi Kuroda, Takafumi Matsumura, Shigeru Ota, Tohru Sugimoto, Yusuke Nakamura, Johji Inazawa; Cloning and characterization of a novel Rab-family gene, Rab36, within the region at 22q11.2 that is homozygously deleted in malignant rhabdoid tumors. Biochem. Biophys. Res. Commun. 254:594-600(1999) PubMed=10417765; DOI=10.1002/(SICI)1097-0215(19990827)82:5<678::AID-IJC10>3.0.CO;2-K Tohru Sugimoto, Hajime Hosoi, Yoshihiro Horii, Hiroyuki Ishida, Hiroshi Mine, Katsuhito Takahashi, Tatsuo Abe, Shigeru Ohta, Tadashi Sawada; Malignant rhabdoid-tumor cell line showing neural and smooth-muscle-cell phenotypes. Int. J. Cancer 82:678-686(1999) PubMed=15355927; DOI=10.1158/1078-0432.CCR-04-0192 Yasumichi Kuwahara, Hajime Hosoi, Shinya Osone, Masakazu Kita, Tomoko Iehara, Hiroshi Kuroda, Tohru Sugimoto; Antitumor activity of gefitinib in malignant rhabdoid tumor cells in vitro and in vivo. Clin. Cancer Res. 10:5940-5948(2004) PubMed=18281554; DOI=10.1158/1078-0432.CCR-07-1661 Yoshiki Katsumi, Yasumichi Kuwahara, Shinichi Tamura, Ken Kikuchi, Osamu Otabe, Kunihiko Tsuchiya, Tomoko Iehara, Hiroshi Kuroda, Hajime Hosoi, Tohru Sugimoto; Trastuzumab activates allogeneic or autologous antibody-dependent cellular cytotoxicity against malignant rhabdoid tumor cells and interleukin-2 augments the cytotoxicity. Clin. Cancer Res. 14:1192-1199(2008) PubMed=21871868; DOI=10.1016/j.bbrc.2011.08.047; PMCID=PMC3214763 Yoshiki Katsumi, Tomoko Iehara, Mitsuru Miyachi, Shigeki Yagyu, Satoko Tsubai-Shimizu, Ken Kikuchi, Shinichi Tamura, Yasumichi Kuwahara, Kunihiko Tsuchiya, Hiroshi Kuroda, Tohru Sugimoto ...Show all 13 authors... , Peter J. Houghton, Hajime Hosoi; Show fewer authors Sensitivity of malignant rhabdoid tumor cell lines to PD 0332991 is inversely correlated with p16 expression. Biochem. Biophys. Res. Commun. 413:62-68(2011) CLPUB00599 Tohru Sugimoto, Hiroshi Kuroda, Yasumichi Kuwahara, Yoshiki Katsumi, Akiko Misawa, Hiroshi Moritake, Hajime Hosoi; Cellular and molecular characteristics of established childhood soft-tissue sarcoma cell lines. J. Cancer Res. Therap. Oncol. 7:202.1-202.12(2019)
Encyclopedic resources	Wikidata; Q54900382
Entry history
Entry creation	04-Apr-2012
Last entry update	29-Jun-2023
Version number	13