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Cellosaurus HA22T/VGH (CVCL_7046)

[Text version]
Cell line name HA22T/VGH
Synonyms Ha22T/VGH; HA 22T/VGH; HA22T
Accession CVCL_7046
Resource Identification Initiative To cite this cell line use: HA22T/VGH (RRID:CVCL_7046)
Comments Population: Chinese.
Karyotypic information: Has lost chromosome Y.
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Omics: Genomics; Mitochondrial genome sequencing.
Misspelling: HA22T/VGF; PubMed=3431441.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg22Glyfs*14 (c.63_85del23); Zygosity=Unspecified (PubMed=7972006).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 52Y
Category Cancer cell line
STR profile Source(s): BCRC=60168

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S8187,12
D7S82011,12
D13S31712
D16S53911
TH017,9
TPOX9,11
vWA14,18

Run an STR similarity search on this cell line
Web pages Provider; Asia Bioscience; GRL-CLC011; https://www.abscience.com.tw/product/ha22t-vgh/
Publications

PubMed=6291875
Yueh-Ming Lin, Cheng-Po Hu, Chen-Kong Chou, Tsai-Wei O-Lee, Kwang-Tong Wuu, Ting-Yao Chen, Fang-Ku P'eng, Tse-Jia Liu, Jone-Long Ko, Chung-Ming Chang;
A new human hepatoma cell line: establishment and characterization.
Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi 15:193-201(1982)

PubMed=6683778; DOI=10.1128/mcb.3.6.1133-1137.1983; PMCID=PMC368642
Chung-Ming Chang, Yueh-Ming Lin, Tsai-Wei O-Lee, Chen-Kung Chou, Tian-Shing Lee, Tse-Jia Liu, Fang-Ku P'eng, Ting-Yao Chen, Cheng-Po Hu;
Induction of plasma protein secretion in a newly established human hepatoma cell line.
Mol. Cell. Biol. 3:1133-1137(1983)

PubMed=3023526; DOI=10.1099/0022-1317-67-11-2315
Sanet Aspinall, Jennifer J. Alexander, Pieter Bos;
Comparative expression of hepatitis B virus antigens in several cell model systems.
J. Gen. Virol. 67:2315-2323(1986)

DOI=10.1007/978-4-431-68349-0_4
Jennifer J. Alexander;
Human hepatoma cell lines.
(In book chapter) Neoplasms of the liver; Okuda, Kunio & Ishak, Kamal George (eds.); pp.47-56; Springer; Tokyo; Japan (1987)

PubMed=2441881; DOI=10.1016/0309-1651(87)90081-6
Sze-Cheng John Lo, Chao-Wen Yang, Cheng-Po Hu, Chung-Ming Chang;
Absence of cytokeratin in human hepatoma cell lines.
Cell Biol. Int. Rep. 11:477-486(1987)

PubMed=3032404; DOI=10.1016/0165-4608(87)90062-8
Kuang-Dong Wuu, Lily Kang, Yuh-Mey Su, Sheng-Wang Wuu, Cheng-Po Hu, Chung-Ming Chang;
Karyotypic characterization of an established human hepatoma cell line HA22T/VGH.
Cancer Genet. Cytogenet. 26:279-286(1987)

PubMed=3431441; DOI=10.1016/s0076-6879(87)51006-0
Gretchen J. Darlington;
Liver cell lines.
Methods Enzymol. 151:19-38(1987)

PubMed=8224613; DOI=10.1096/fasebj.7.14.8224613
Alain Puisieux, Katherine Galvin, Frederic Troalen, Brigitte Bressac, Christophe Marcais, Eithan Galun, Frederique Ponchel, Cengiz Yakicier, Jing-Wei Ji, Mehmet Ozturk;
Retinoblastoma and p53 tumor suppressor genes in human hepatoma cell lines.
FASEB J. 7:1407-1413(1993)

PubMed=7972006; DOI=10.1073/pnas.91.23.11045; PMCID=PMC45163
Aikou Okamoto, Douglas J. Demetrick, Elisa A. Spillare, Koichi Hagiwara, S. Perwez Hussain, William P. Bennett, Kathleen Forrester, Brenda Isen Gerwin, Manuel Serrano, David H. Beach, Curtis Craig Harris;
Mutations and altered expression of p16INK4 in human cancer.
Proc. Natl. Acad. Sci. U.S.A. 91:11045-11049(1994)

PubMed=8050184; DOI=10.1111/j.1365-2249.1994.tb06089.x; PMCID=PMC1534706
Ahmed Abdulhay Wadee, Alan Paterson, Keren Anne Coplan, Selvan G. Reddy;
HLA expression in hepatocellular carcinoma cell lines.
Clin. Exp. Immunol. 97:328-333(1994)

PubMed=29051253; DOI=10.1128/genomeA.01136-17; PMCID=PMC5646406
Deng-Gao Huang, Gang Cheng, Jin-Cai Wu;
Complete mitochondrial genome of the human liver cancer HA22T cell line.
Genome Announc. 5:e01136.17.1-e01136.17.2(2017)

Cross-references
Cell line collections (Providers) BCRC; 60168
Anatomy/cell type resources BTO; BTO_0002429
Chemistry resources ChEMBL-Cells; CHEMBL3308657
ChEMBL-Targets; CHEMBL614807
PubChem_Cell_line; CVCL_7046
Encyclopedic resources Wikidata; Q54872284
Polymorphism and mutation databases Cosmic; 932991
Cosmic; 934552
Cosmic; 2668280
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number25