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Cellosaurus GR-Mel (CVCL_7045)

[Text version]
Cell line name GR-Mel
Accession CVCL_7045
Resource Identification Initiative To cite this cell line use: GR-Mel (RRID:CVCL_7045)
Comments Microsatellite instability: Stable (MSS) (PubMed=11851879).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=11121133; DOI=10.1046/j.1523-1747.2000.00199.x
Lacal P.M., Failla C.M., Pagani E., Odorisio T., Schietroma C., Falcinelli S., Zambruno G., D'Atri S.
Human melanoma cells secrete and respond to placenta growth factor and vascular endothelial growth factor.
J. Invest. Dermatol. 115:1000-1007(2000)

PubMed=11851879; DOI=10.1046/j.0022-202x.2001.01611.x
Alvino E., Marra G., Pagani E., Falcinelli S., Pepponi R., Perrera C., Haider R., Castiglia D., Ferranti G., Bonmassar E., Jiricny J., Zambruno G., D'Atri S.
High-frequency microsatellite instability is associated with defective DNA mismatch repair in human melanoma.
J. Invest. Dermatol. 118:79-86(2002)

PubMed=18384130; DOI=10.1002/gcc.20567
Castiglia D., Bernardini S., Alvino E., Pagani E., De Luca N., Falcinelli S., Pacchiarotti A., Bonmassar E., Zambruno G., D'Atri S.
Concomitant activation of Wnt pathway and loss of mismatch repair function in human melanoma.
Genes Chromosomes Cancer 47:614-624(2008)

PubMed=19799798; DOI=10.1186/1471-2407-9-352; PMCID=PMC2763007
Casula M., Muggiano A., Cossu A., Budroni M., Caraco C., Ascierto P.A., Pagani E., Stanganelli I., Canzanella S., Sini M.C., Palomba G., Palmieri G.
Italian Melanoma Intergroup (IMI)
Role of key-regulator genes in melanoma susceptibility and pathogenesis among patients from South Italy.
BMC Cancer 9:352.1-352.11(2009)

PubMed=21424129; DOI=10.3892/or.2011.1220
Manca A., Sini M.C., Izzo F., Ascierto P.A., Tatangelo F., Botti G., Gentilcore G., Capone M., Mozzillo N., Rozzo C., Cossu A., Tanda F., Palmieri G.
Induction of arginosuccinate synthetase (ASS) expression affects the antiproliferative activity of arginine deiminase (ADI) in melanoma cells.
Oncol. Rep. 25:1495-1502(2011)

PubMed=29492214; DOI=10.18632/oncotarget.23989; PMCID=PMC5823576
Sini M.C., Doneddu V., Paliogiannis P., Casula M., Colombino M., Manca A., Botti G., Ascierto P.A., Lissia A., Cossu A., Palmieri G.
Genetic alterations in main candidate genes during melanoma progression.
Oncotarget 9:8531-8541(2018)

Cross-references
Encyclopedic resources Wikidata; Q54871657
Polymorphism and mutation databases Cosmic; 1109806
Cosmic; 1295327
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number9