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Cellosaurus HCK (CVCL_6F04)

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Cell line name HCK
Synonyms Human Corneal Keratocytes
Accession CVCL_6F04
Resource Identification Initiative To cite this cell line use: HCK (RRID:CVCL_6F04)
Comments Doubling time: 34 hours (PubMed=15813699).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Eye, cornea; UBERON=UBERON_0000964.
Cell type: Keratocyte; CL=CL_0002363.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=15813699; DOI=10.1177/026119290503300107
Michaela Zorn-Kruppa, Svitlana Tykhonova, Gazanfer Belge, Jurgen Bednarz, Horst A. Diehl, Maria Engelke;
A human corneal equivalent constructed from SV40-immortalised corneal cell lines.
Altern. Lab. Anim. 33:37-45(2005)

PubMed=19326031; DOI=10.14573/altex.2009.1.33
Anna Katharina Manzer, Simone Lombardi-Borgia, Monika Schafer-Korting, Judith Seeber, Michaela Zorn-Kruppa, Maria Engelke;
SV40-transformed human corneal keratocytes: optimisation of serum-free culture conditions.
ALTEX 26:33-39(2009)

Cross-references
Cell line databases/resources FCS-free; 4-2-4-2-4-3
FCS-free; 4-2-6-1-4-3
Encyclopedic resources Wikidata; Q54881880
Entry history
Entry creation23-Feb-2016
Last entry update27-Nov-2025
Version number9