| Cell line name |
LNCaP C4-2Pr |
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| Synonyms |
C4-2Pr; C4-2 Pr; C4-2 Primary tumor |
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| Accession |
CVCL_6E93 |
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| Resource Identification Initiative |
To cite this cell line use: LNCaP C4-2Pr (RRID:CVCL_6E93) |
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| Comments |
Population: Caucasian.
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056. |
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| Sequence variations |
- Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
- Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
|
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| Disease |
Prostate carcinoma (NCIt: C4863) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_4782 (LNCaP C4-2) |
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| Sex of cell |
Male |
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| Age at sampling |
50Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=8168083
George Niklaus Thalmann, Ploutarchos E. Anezinis, Shi-Ming Chang, Hai-Yen E. Zhau, E. Edmund Kim, Vicki Lee Hopwood, Sen Pathak, Andrew C. von Eschenbach, Leland W.K. Chung;
Androgen-independent cancer progression and bone metastasis in the LNCaP model of human prostate cancer.
Cancer Res. 54:2577-2581(1994) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_6E93
|
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| Encyclopedic resources |
Wikidata; Q54902821
|
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| Entry history |
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| Entry creation | 23-Feb-2016 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 13 |
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