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Cellosaurus LNCaP C4-2Ln (CVCL_6E92)

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Cell line name LNCaP C4-2Ln
Synonyms C4-2Ln; C4-2 Ln; C4-2 Lymph node metastasis
Accession CVCL_6E92
Resource Identification Initiative To cite this cell line use: LNCaP C4-2Ln (RRID:CVCL_6E92)
Comments Population: Caucasian.
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4782 (LNCaP C4-2)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=8168083
George Niklaus Thalmann, Ploutarchos E. Anezinis, Shi-Ming Chang, Hai-Yen E. Zhau, E. Edmund Kim, Vicki Lee Hopwood, Sen Pathak, Andrew C. von Eschenbach, Leland W.K. Chung;
Androgen-independent cancer progression and bone metastasis in the LNCaP model of human prostate cancer.
Cancer Res. 54:2577-2581(1994)

Cross-references
Cell line databases/resources cancercelllines; CVCL_6E92
Encyclopedic resources Wikidata; Q54902820
Entry history
Entry creation23-Feb-2016
Last entry update19-Dec-2024
Version number13