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Cellosaurus MCF-10A-neoN (CVCL_6C55)

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Cell line name MCF-10A-neoN
Synonyms MCF-10A neoN; MCF-10AneoN; MCF10AneoN
Accession CVCL_6C55
Resource Identification Initiative To cite this cell line use: MCF-10A-neoN (RRID:CVCL_6C55)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:5173; HRAS.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0598 (MCF-10A)
Sex of cell Female
Age at sampling 36Y
Category Spontaneously immortalized cell line
Publications

PubMed=1885681; DOI=10.1242/jcs.99.2.453
Jose Russo, Larry Tait, Irma Haydee Russo;
Morphological expression of cell transformation induced by c-Ha-ras oncogene in human breast epithelial cells.
J. Cell Sci. 99:453-463(1991)

PubMed=2009132; DOI=10.1002/mc.2940040106
Fulvio Basolo, James Elliott, Larry Tait, Xiao-Qin Chen, Terry M. Maloney, Irma Haydee Russo, Robert J. Pauley, Shigeru Momiki, Jorge Caamano, Andres J.P. Klein-Szanto, Maria Koszalka, Jose Russo;
Transformation of human breast epithelial cells by c-Ha-ras oncogene.
Mol. Carcinog. 4:25-35(1991)

Cross-references
Encyclopedic resources Wikidata; Q54904296
Entry history
Entry creation23-Feb-2016
Last entry update14-Aug-2025
Version number12