Cellosaurus cell line MCF-10A-neo (CVCL

Cross-references
Cell line name	MCF-10A-neo
Synonyms	MCF-10A neo; MCF-10ANeo; MCF10A-neo; MCF10Aneo
Accession	CVCL_6C54
Resource Identification Initiative	To cite this cell line use: MCF-10A-neo (RRID:CVCL_6C54)
Comments	Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0598 (MCF-10A)
Sex of cell	Female
Age at sampling	36Y
Category	Spontaneously immortalized cell line
Publications	PubMed=1885681; DOI=10.1242/jcs.99.2.453 Jose Russo, Larry Tait, Irma Haydee Russo; Morphological expression of cell transformation induced by c-Ha-ras oncogene in human breast epithelial cells. J. Cell Sci. 99:453-463(1991) PubMed=2009132; DOI=10.1002/mc.2940040106 Fulvio Basolo, James Elliott, Larry Tait, Xiao-Qin Chen, Terry M. Maloney, Irma Haydee Russo, Robert J. Pauley, Shigeru Momiki, Jorge Caamano, Andres J.P. Klein-Szanto, Maria Koszalka, Jose Russo; Transformation of human breast epithelial cells by c-Ha-ras oncogene. Mol. Carcinog. 4:25-35(1991)
Encyclopedic resources	Wikidata; Q54904295
Entry history
Entry creation	23-Feb-2016
Last entry update	14-Aug-2025
Version number	12