Cellosaurus logo
expasy logo

Cellosaurus HC2S2 (CVCL_6A80)

[Text version]
Cell line name HC2S2
Accession CVCL_6A80
Resource Identification Initiative To cite this cell line use: HC2S2 (RRID:CVCL_6A80)
Comments Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P01110; Avian myelocytomatosis virus MC29 v-Myc.
Transformant: v-Myc.
Derived from site: In situ; Brain, hippocampus; UBERON=UBERON_0002421.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS_0000215.
Sex of cell Sex unspecified
Age at sampling 3M
Category Conditionally immortalized cell line
Publications

PubMed=8643664; DOI=10.1073/pnas.93.4.1518; PMCID=PMC39972
Hoshimaru M., Ray J., Sah D.W.Y., Gage F.H.
Differentiation of the immortalized adult neuronal progenitor cell line HC2S2 into neurons by regulatable suppression of the v-myc oncogene.
Proc. Natl. Acad. Sci. U.S.A. 93:1518-1523(1996)

PubMed=9634594; DOI=10.1007/s004410051094
Ohtsuka T., Asahi M., Matsuura N., Kikuchi H., Hojo M., Kageyama R., Ohkubo H., Hoshimaru M.
Regulated expression of neurogenic basic helix-loop-helix transcription factors during differentiation of the immortalized neuronal progenitor cell line HC2S2 into neurons.
Cell Tissue Res. 293:23-29(1998)

Cross-references
Encyclopedic resources Wikidata; Q54881481
Entry history
Entry creation23-Feb-2016
Last entry update10-Apr-2025
Version number7