Cellosaurus cell line HC2S2 (CVCL

Cross-references
Cell line name	HC2S2
Accession	CVCL_6A80
Resource Identification Initiative	To cite this cell line use: HC2S2 (RRID:CVCL_6A80)
Comments	Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P01110; Avian myelocytomatosis virus 29 v-Myc. Transformant: v-Myc. Derived from site: In situ; Brain, hippocampus; UBERON=UBERON_0002421.
Species of origin	Rattus norvegicus (Rat) (NCBI Taxonomy: 10116) Breed/subspecies: Fischer 344; RS=RS_0000215.
Sex of cell	Sex unspecified
Age at sampling	3M
Category	Conditionally immortalized cell line
Publications	PubMed=8643664; DOI=10.1073/pnas.93.4.1518; PMCID=PMC39972 Minoru Hoshimaru, Jasodhara Ray, Dinah W.Y. Sah, Fred Harrison Gage; Differentiation of the immortalized adult neuronal progenitor cell line HC2S2 into neurons by regulatable suppression of the v-myc oncogene. Proc. Natl. Acad. Sci. U.S.A. 93:1518-1523(1996) PubMed=9634594; DOI=10.1007/s004410051094 Toshiyuki Ohtsuka, Minoru Asahi, Nobuki Matsuura, Haruhiko Kikuchi, Masato Hojo, Ryoichiro Kageyama, Hiroaki Ohkubo, Minoru Hoshimaru; Regulated expression of neurogenic basic helix-loop-helix transcription factors during differentiation of the immortalized neuronal progenitor cell line HC2S2 into neurons. Cell Tissue Res. 293:23-29(1998)
Encyclopedic resources	Wikidata; Q54881481
Entry history
Entry creation	23-Feb-2016
Last entry update	14-Aug-2025
Version number	8