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Cellosaurus MDA-1386 (CVCL_6979)

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Cell line name MDA-1386
Synonyms MDA 1386; MDA1386
Accession CVCL_6979
Resource Identification Initiative To cite this cell line use: MDA-1386 (RRID:CVCL_6979)
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Pro (c.838_839AG>CC); Zygosity=Unspecified (PubMed=7927946).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Unspecified (PubMed=7927946).
Disease Hypopharyngeal squamous cell carcinoma (NCIt: C4043)
Squamous cell carcinoma of the hypopharynx (ORDO: Orphanet_494547)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_H541 ! MDA-1386Ln
CVCL_H542 ! MDA-1386Tu
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
Publications

PubMed=7927946; DOI=10.1002/ijc.2910590316
Li Xu, Bruce J. Davidson, Vundavalli V.V.S. Murty, Rong-Guo Li, Peter G. Sacks, Pilar Garin-Chesa, Stimson P. Schantz, Raju S.K. Chaganti;
TP53 gene mutations and CCND1 gene amplification in head and neck squamous cell carcinoma cell lines.
Int. J. Cancer 59:383-387(1994)

PubMed=11389082
Bhuvanesh Singh, Swarna K. Gogineni, Peter G. Sacks, Ashok R. Shaha, Jatin P. Shah, Archontoula Stoffel, Pulivarthi H. Rao;
Molecular cytogenetic characterization of head and neck squamous cell carcinoma and refinement of 3q amplification.
Cancer Res. 61:4506-4513(2001)

Cross-references
Cell line databases/resources cancercelllines; CVCL_6979
Encyclopedic resources Wikidata; Q54904550
Polymorphism and mutation databases IARC_TP53; 3547
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number16