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Cellosaurus MDA-183 (CVCL_6978)

[Text version]

Cell line name MDA-183
Synonyms MDA 183; MDA183; MDA-183A; Line 183; 183; 183A
Accession CVCL_6978
Resource Identification Initiative To cite this cell line use: MDA-183 (RRID:CVCL_6978)
Comments Doubling time: ~36 hours (PubMed=2452013).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: Protein expression by reverse-phase protein arrays.
Disease Tonsillar squamous cell carcinoma (NCIt: C8183)
Squamous cell carcinoma of the oropharynx (ORDO: Orphanet_500478)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): PubMed=21868764

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81810,13
D7S8209
D13S31711,12
D16S53913
TH016
TPOX8
vWA18

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Publications

PubMed=2452013
Sacks P.G., Parnes S.M., Gallick G.E., Mansouri Z., Lichtner R., Satya-Prakash K.L., Pathak S., Parsons D.F.
Establishment and characterization of two new squamous cell carcinoma cell lines derived from tumors of the head and neck.
Cancer Res. 48:2858-2866(1988)

DOI=10.1016/B978-0-12-333530-2.50007-1
Carey T.E.
Head and neck tumor cell lines.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.79-120; Academic Press; New York (1994)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690
Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C., Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G., Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

PubMed=29156801; DOI=10.18632/oncotarget.21174
Kalu N.N., Mazumdar T., Peng S., Shen L., Sambandam V., Rao X., Xi Y., Li L., Qi Y., Gleber-Netto F.O., Patel A., Wang J., Frederick M.J., Myers J.N., Pickering C.R., Johnson F.M.
Genomic characterization of human papillomavirus-positive and -negative human squamous cell cancer cell lines.
Oncotarget 8:86369-86383(2017)

Cross-references
Encyclopedic resources Wikidata; Q54904557
Polymorphism and mutation databases Cosmic; 948036
Cosmic; 2602600
Entry history
Entry creation04-Apr-2012
Last entry update12-Mar-2020
Version number14