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Cellosaurus MDA-183 (CVCL_6978)

[Text version]
Cell line name MDA-183
Synonyms MDA 183; MDA183; MDA-183A; Line 183; 183; 183A
Accession CVCL_6978
Resource Identification Initiative To cite this cell line use: MDA-183 (RRID:CVCL_6978)
Comments Doubling time: ~36 hours (PubMed=2452013).
Omics: Genomics; Whole exome sequencing.
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Oral cavity, tonsil; UBERON=UBERON_0002372.
Disease Tonsillar squamous cell carcinoma (NCIt: C8183)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): PubMed=21868764

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81810,13
D7S8209
D13S31711,12
D16S53913
TH016
TPOX8
vWA18

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Publications

PubMed=2452013
Peter G. Sacks, Steven Mark Parnes, Gary E. Gallick, Zahra Mansouri, Rosemarie Lichtner, Kanithahalli L. Satya-Prakash, Sen Pathak, Donald F. Parsons;
Establishment and characterization of two new squamous cell carcinoma cell lines derived from tumors of the head and neck.
Cancer Res. 48:2858-2866(1988)

DOI=10.1016/B978-0-12-333530-2.50007-1
Thomas E. Carey;
Head and neck tumor cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.79-120; Academic Press; New York; USA (1994)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662
Mei Zhao, Daisuke Sano, Curtis R. Pickering, Samar A. Jasser, Ying C. Henderson, Gary L. Clayman, Erich M. Sturgis, Thomas J. Ow, Reuben Lotan, Thomas E. Carey, Peter G. Sacks ...Show all 15 authors... , Jennifer Rubin Grandis, David Sidransky, Nils-Erik Heldin, Jeffrey N. Myers; Show fewer authors
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

PubMed=29156801; DOI=10.18632/oncotarget.21174; PMCID=PMC5689691
Nene N. Kalu, Tuhina Mazumdar, Shao-Hua Peng, Li Shen, Vaishnav Sambandam, Xia-Yu Rao, Yuan-Xin Xi, Le-Rong Li, Yuan Qi, Frederico O. Gleber-Netto, Ameeta Patel ...Show all 16 authors... , Jing Wang, Mitchell J. Frederick, Jeffrey N. Myers, Curtis R. Pickering, Faye M. Johnson; Show fewer authors
Genomic characterization of human papillomavirus-positive and -negative human squamous cell cancer cell lines.
Oncotarget 8:86369-86383(2017)

Cross-references
Encyclopedic resources Wikidata; Q54904557
Polymorphism and mutation databases Cosmic; 948036
Cosmic; 2602600
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number17