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Cellosaurus CoC1/DDP (CVCL_6892)

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Cell line name CoC1/DDP
Synonyms COC1/DDP
Accession CVCL_6892
Resource Identification Initiative To cite this cell line use: CoC1/DDP (RRID:CVCL_6892)
Comments Population: Chinese.
Doubling time: 27 hours (PubMed=9275551).
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Omics: Proteomics; 2DE-MS.
Omics: Transcriptomics; Microarray.
Disease Ovarian adenocarcinoma (NCIt: C7700)
Adenocarcinoma of ovary (ORDO: Orphanet_213504)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6891 (CoC1)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): CCRID=4201HUM-CCTCC00058

Markers:
AmelogeninX
CSF1PO11
D2S133824
D3S135815,20
D5S81812,13
D7S8209,13,14
D8S117912,13
D13S31711,12
D16S53910,12,13
D18S5112,18
D19S43314,15
D21S1130,33.2
FGA23,24
TH016,7
TPOX8
vWA16,17,20

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Publications

PubMed=9275551
You-Zhen Zhou, Hui-Zhen Chen, Qin-Yi Yang, Shi-Quan Liu, Han-Ying Hou;
Establishment of human ovarian cancer cisplatin resistant cell line COC1/DDP and its mechanism of resistance.
Zhonghua Yi Xue Za Zhi 76:680-683(1996)

PubMed=23464471; DOI=10.7314/APJCP.2012.13.12.6435
Jing Zhou, Yue-Hua Wei, Mei-Yan Liao, Yan Xiong, Jie-Lan Li, Hong-Bing Cai;
Identification of cisplatin-resistance associated genes through proteomic analysis of human ovarian cancer cells and a cisplatin-resistant subline.
Asian Pac. J. Cancer Prev. 13:6435-6439(2012)

PubMed=25502083; DOI=10.1007/s12032-014-0426-5; PMCID=PMC4262766
Lian-Cheng Zhu, Zhen-Hua Hu, Juan-Juan Liu, Jian Gao, Bei Lin;
Gene expression profile analysis identifies metastasis and chemoresistance-associated genes in epithelial ovarian carcinoma cells.
Med. Oncol. 32:426.1-426.13(2015)

Cross-references
Cell line collections (Providers) CCTCC; GDC0058
Cell line databases/resources CCRID; 4201HUM-CCTCC00058
Encyclopedic resources Wikidata; Q54813959
Entry history
Entry creation04-Apr-2012
Last entry update27-Nov-2025
Version number20