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Cellosaurus ACC-3 (CVCL_6873)

[Text version]
Cell line name ACC-3
Synonyms Acc-3; ACC3
Accession CVCL_6873
Resource Identification Initiative To cite this cell line use: ACC-3 (RRID:CVCL_6873)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=19557180; PubMed=20143388; PubMed=21868764). Originally thought to originate from a 49 year old male patient with a salivary gland adenoid cystic carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00358.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): PubMed=21868764

Markers:
AmelogeninX
CSF1PO9,10
D5S81811,12
D7S8208,12
D13S31712,13.3
D16S5399,10
TH017
TPOX8,12
vWA17,18

Run an STR similarity search on this cell line
Web pages Info; ACCRF; -; https://web.archive.org/web/20110617125837/http://www.accrf.org/pdf/accrf_update_march2009.pdf
Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=10359046; DOI=10.1111/j.1349-7006.1999.tb00749.x; PMCID=PMC5926065
Koh-ei Toyoshima, Shinn Kimura, Jun Cheng, Yohei Oda, Kazuhiro John Mori, Takashi Saku;
High-molecular-weight fibronectin synthesized by adenoid cystic carcinoma cells of salivary gland origin.
Jpn. J. Cancer Res. 90:308-319(1999)

PubMed=19557180; DOI=10.1371/journal.pone.0006040; PMCID=PMC2698276
Janyaporn Phuchareon, Yoshihito Ohta, Jonathan M. Woo, David William Eisele, Osamu Tetsu;
Genetic profiling reveals cross-contamination and misidentification of 6 adenoid cystic carcinoma cell lines: ACC2, ACC3, ACCM, ACCNS, ACCS and CAC2.
PLoS ONE 4:e6040.1-e6040.8(2009)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662
Mei Zhao, Daisuke Sano, Curtis R. Pickering, Samar A. Jasser, Ying C. Henderson, Gary L. Clayman, Erich M. Sturgis, Thomas J. Ow, Reuben Lotan, Thomas E. Carey, Peter G. Sacks ...Show all 15 authors... , Jennifer Rubin Grandis, David Sidransky, Nils-Erik Heldin, Jeffrey N. Myers; Show fewer authors
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

DOI=10.4103/2468-5585.200513
Nan-Nan Liu, Sen-Lin Zhang, Wei Chen;
The cross-contaminated cell lines of adenoid cystic carcinoma: a crucial concern.
Transl. Surg. 2:10-13(2017)

Cross-references
Biological sample resources BioSample; SAMN03151660
Encyclopedic resources Wikidata; Q54608099
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number27