Cellosaurus cell line RNK-16 (CVCL

Cellosaurus RNK-16 (CVCL_6849)

Cross-references
Cell line name	RNK-16
Synonyms	RNK16; CRNK-16; Rat Natural Killer-16
Accession	CVCL_6849
Resource Identification Initiative	To cite this cell line use: RNK-16 (RRID:CVCL_6849)
Comments	Derived from site: In situ; Spleen; UBERON=UBERON_0002106. Cell type: Natural killer cell; CL=CL_0000623.
Disease	Rat large granular lymphocyte leukemia (NCIt: C64066)
Species of origin	Rattus norvegicus (Rat) (NCBI Taxonomy: 10116) Breed/subspecies: Fischer 344; RS=RS_0000215.
Sex of cell	Male
Age at sampling	Adult
Category	Cancer cell line
Web pages	Info; -; -; https://web.archive.org/web/20141104152235/http://www2.kumc.edu/soalab/LabLinks/cell%20lines/rnk16.htm
Publications	PubMed=6837719; PMCID=PMC1916195 Jerrold M. Ward, Craig W. Reynolds; Large granular lymphocyte leukemia. A heterogeneous lymphocytic leukemia in F344 rats. Am. J. Pathol. 111:1-10(1983) PubMed=6197459; DOI=10.4049/jimmunol.132.1.534 Craig W. Reynolds, E. William Bere Jr., Jerrold M. Ward; Natural killer activity in the rat. III. Characterization of transplantable large granular lymphocyte (LGL) leukemias in the F344 rat. J. Immunol. 132:534-540(1984) PubMed=8133042; DOI=10.4049/jimmunol.152.5.2289 Thomas J. Sayers, Theresa A. Wiltrout, Mark John Smyth, Kimberley S. Ottaway, Anne M. Pilaro, Raymond C. Sowder, Louis E. Henderson, Hans Sprenger, Andrew R. Lloyd; Purification and cloning of a novel serine protease, RNK-Tryp-2, from the granules of a rat NK cell leukemia. J. Immunol. 152:2289-2297(1994) PubMed=16465528; DOI=10.1007/s00262-006-0139-5; PMCID=PMC11031106 Roi Avraham, Shelly Inbar, Ella Rosenne, Shamgar Ben-Eliyahu; Autologous control of a highly malignant syngeneic CRNK-16 leukemia in the rat: a role for NK cells. Cancer Immunol. Immunother. 55:1348-1357(2006)
Anatomy/cell type resources	BTO; BTO_0002031
Encyclopedic resources	Wikidata; Q54950768
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Apr-2025
Version number	13