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Cellosaurus LN-382T (CVCL_6839)

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Cell line name LN-382T
Synonyms LN 382T; LN382T
Accession CVCL_6839
Resource Identification Initiative To cite this cell line use: LN-382T (RRID:CVCL_6839)
Comments Population: Caucasian.
Derived from site: In situ; Brain, right fronto-parietal lobe.
Sequence variations
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Arg320Ter (c.958C>T); ClinVar=VCV000126824; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val197Leu (c.589G>T); ClinVar=VCV000216468; Zygosity=Homozygous (PubMed=10416987).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3956 (LN-382)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line
STR profile Source(s): PubMed=22570425

Markers:
AmelogeninX
CSF1PO10,11
D3S135814,18
D5S81811
D7S8208,11
D8S11799,13
D13S31713
D16S5399,12
D18S5115,16
D21S1130,31.2
FGA24,25
Penta D12
Penta E10
TH019,9.3
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=10416987; DOI=10.1111/j.1750-3639.1999.tb00536.x; PMCID=PMC8098486
Nobuaki Ishii, Daniel Maier, Adrian Merlo, Mitsuhiro Tada, Yutaka Sawamura, Annie-Claire Diserens, Erwin G. Van Meir;
Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines.
Brain Pathol. 9:469-479(1999)

PubMed=22570425; DOI=10.1093/neuonc/nos072; PMCID=PMC3367844
Pierre Bady, Annie-Claire Diserens, Vincent Castella, Stefanie Kalt, Karl Heinimann, Marie-France Hamou, Mauro Delorenzi, Monika E. Hegi;
DNA fingerprinting of glioma cell lines and considerations on similarity measurements.
Neuro-oncol. 14:701-711(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_6839
Encyclopedic resources Wikidata; Q54902779
Polymorphism and mutation databases Cosmic; 849866
Cosmic; 2367495
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number18