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Cellosaurus WM3248 (CVCL_6798)

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Cell line name WM3248
Synonyms WM-3248; WM 3248; WC00081
Accession CVCL_6798
Resource Identification Initiative To cite this cell line use: WM3248 (RRID:CVCL_6798)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptomics; Microarray.
Misspelling: WM-3428; Cosmic=1303073.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (Wistar).
  • Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (Wistar).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Homozygous (Wistar).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys144Ter (c.430A>T); ClinVar=VCV000379501; Zygosity=Homozygous (Wistar).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Web pages Info; Wistar; -; https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Keith S. Hoek, Natalie C. Schlegel, Patricia Brafford, Antje Sucker, Selma Ugurel, Rajiv Kumar, Barbara L. Weber, Katherine L. Nathanson, Donald J. Phillips, Meenhard Herlyn, Dirk Schadendorf, Reinhard Dummer;
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235; PMCID=PMC2615688
Keiran S.M. Smalley, Rooha Contractor, Thiennga K. Nguyen, Min Xiao, Robin Edwards, Viswanathan Muthusamy, Alastair J. King, Keith Thomas Flaherty, Marcus W. Bosenberg, Meenhard Herlyn, Katherine L. Nathanson;
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res. 68:5743-5752(2008)

Cross-references
Cell line collections (Providers) Coriell; WC00081 - Discontinued
Rockland; WM3248-01-0001
Cell line databases/resources cancercelllines; CVCL_6798
Encyclopedic resources Wikidata; Q54994244
Gene expression databases GEO; GSM109037
GEO; GSM185196
GEO; GSM185197
GEO; GSM188066
GEO; GSM188118
GEO; GSM188191
GEO; GSM188206
GEO; GSM188215
GEO; GSM188234
GEO; GSM188264
GEO; GSM188282
GEO; GSM188291
GEO; GSM188323
Polymorphism and mutation databases Cosmic; 1155546
Cosmic; 1303073
Progenetix; CVCL_6798
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number24