Cellosaurus logo
expasy logo

Cellosaurus WM3211 (CVCL_6797)

[Text version]
Cell line name WM3211
Synonyms WM-3211; WM 3211; WC00045; EST79
Accession CVCL_6797
Resource Identification Initiative To cite this cell line use: WM3211 (RRID:CVCL_6797)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: Wistar Institute melanoma cell line collection.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
HLA typing Source: PubMed=15592718
Class I
HLA-AA*03:01,24:02
HLA-BB*07:02
HLA-CC*07:02
Class II
HLA-DPDPB1*04:01
HLA-DQDQB1*06:02,03:01:01
HLA-DRDRB1*04:01:01,15:01
Disease Acral lentiginous melanoma (NCIt: C4022)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 34Y
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-079; Wistar

Markers:
AmelogeninX
CSF1PO13
D2S133820,24
D3S135815,16
D5S81811
D7S82010,12
D8S117910,11
D13S31712
D16S53912
D18S5112
D19S43313,14
D21S1129,31.2
FGA20
TH016,9.3
TPOX11
vWA14,17

Run an STR similarity search on this cell line
Web pages Info; Wistar; -; https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966
Teresa Rodriguez, Rosa Mendez, Chrissy H. Roberts, Francisco Ruiz-Cabello Osuna, I. Anthony Dodi, Miguel Angel Lopez-Nevot, Laura Paco, Isabel Maleno, Steven G.E. Marsh, Graham Pawelec, Federico Garrido;
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Keith S. Hoek, Natalie C. Schlegel, Patricia Brafford, Antje Sucker, Selma Ugurel, Rajiv Kumar, Barbara L. Weber, Katherine L. Nathanson, Donald J. Phillips, Meenhard Herlyn, Dirk Schadendorf, Reinhard Dummer;
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=17260012; DOI=10.1038/sj.onc.1210252
Goran Jonsson, Christina Dahl, Johan Staaf, Troy Sandberg, Par-Ola Bendahl, Markus Ringner, Per Guldberg, Ake Borg;
Genomic profiling of malignant melanoma using tiling-resolution arrayCGH.
Oncogene 26:4738-4748(2007)

PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235; PMCID=PMC2615688
Keiran S.M. Smalley, Rooha Contractor, Thiennga K. Nguyen, Min Xiao, Robin Edwards, Viswanathan Muthusamy, Alastair J. King, Keith Thomas Flaherty, Marcus W. Bosenberg, Meenhard Herlyn, Katherine L. Nathanson;
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res. 68:5743-5752(2008)

PubMed=22578220; DOI=10.1111/j.1755-148X.2012.01016.x
Simon J. Furney, Samra Turajlic, Kerry Fenwick, Maryou B. Lambros, Alan Mackay, Gerda Ricken, Costas Mitsopoulos, Iwanka Kozarewa, Jarle Hakas, Marketa Zvelebil, Christopher J. Lord ...Show all 16 authors... , Alan Ashworth, Jorge Sergio Reis-Filho, Meenhard Herlyn, Hiroshi Murata, Richard Marais; Show fewer authors
Genomic characterisation of acral melanoma cell lines.
Pigment Cell Melanoma Res. 25:488-492(2012)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Christina Dahl, Claus Christensen, Goran Jonsson, Anders Lorentzen, Mette Louise Skjodt, Ake Borg, Graham Pawelec, Per Guldberg;
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

PubMed=24576830; DOI=10.1158/0008-5472.CAN-13-2625; PMCID=PMC4005042
Moriah Heller Nissan, Christine A. Pratilas, Alexis M. Jones, Ricardo Ramirez, Helen Won, Cai-Lian Liu, Shakuntala Tiwari, Li Kong, Aphrothiti J. Hanrahan, Zhan Yao, Taha Merghoub ...Show all 19 authors... , Antoni Ribas, Paul B. Chapman, Rona D. Yaeger, Barry Stephen Taylor, Nikolaus Schultz, Michael F. Berger, Neal Rosen, David B. Solit; Show fewer authors
Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence.
Cancer Res. 74:2340-2350(2014)

Cross-references
Cell line collections (Providers) Coriell; WC00045 - Discontinued
Rockland; WM3211-01-0001
Cell line databases/resources cancercelllines; CVCL_6797
DepMap; ACH-002508
ESTDAB; ESTDAB-079
Encyclopedic resources Wikidata; Q54994241
Gene expression databases GEO; GSM109036
GEO; GSM156008
GEO; GSM185194
GEO; GSM185195
GEO; GSM188070
GEO; GSM188122
GEO; GSM188195
GEO; GSM188210
GEO; GSM188216
GEO; GSM188233
GEO; GSM188263
GEO; GSM188286
GEO; GSM188295
GEO; GSM188322
Polymorphism and mutation databases Cosmic; 972286
Cosmic; 1047655
Cosmic; 1155289
Cosmic; 1155541
Cosmic; 1284919
Cosmic; 1303071
Cosmic; 2144978
Cosmic; 2159443
Cosmic; 2163806
IARC_TP53; 26082
Progenetix; CVCL_6797
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number35