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Cellosaurus WM1361A (CVCL_6788)

[Text version]
Cell line name WM1361A
Synonyms WM-1361A; WM 1361A; WC00075; EST69
Accession CVCL_6788
Resource Identification Initiative To cite this cell line use: WM1361A (RRID:CVCL_6788)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=17260012; Wistar).
  • Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (Wistar).
  • Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Hemizygous (Wistar).
  • Mutation; HGNC; HGNC:1097; BRAF; None_reported; -; Zygosity=- (Wistar).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Homozygous (PubMed=17260012; PubMed=23851445; Wistar).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_6993 ! WM1361B
CVCL_6994 ! WM1361C
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-069; Wistar

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S133825
D3S135816
D5S81811
D7S8208,10
D8S117912,13
D13S31711
D16S53911,12
D18S5114
D19S43313,14
D21S1130,31.2
FGA22,25
TH017 (Wistar)
7,8 (ESTDAB=ESTDAB-069)
TPOX8,11
vWA14,17

Run an STR similarity search on this cell line
Web pages Info; Wistar; -; https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=2253310; DOI=10.1007/BF00046337
Meenhard Herlyn;
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

PubMed=2068080; DOI=10.1073/pnas.88.14.6028; PMCID=PMC52015
Isabelle Cornil, Dan Theodorescu, Shan Man, Meenhard Herlyn, Jadranka Adriana Jambrosic, Robert S. Kerbel;
Fibroblast cell interactions with human melanoma cells affect tumor cell growth as a function of tumor progression.
Proc. Natl. Acad. Sci. U.S.A. 88:6028-6032(1991)

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Keith S. Hoek, Natalie C. Schlegel, Patricia Brafford, Antje Sucker, Selma Ugurel, Rajiv Kumar, Barbara L. Weber, Katherine L. Nathanson, Donald J. Phillips, Meenhard Herlyn, Dirk Schadendorf, Reinhard Dummer;
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=17260012; DOI=10.1038/sj.onc.1210252
Goran Jonsson, Christina Dahl, Johan Staaf, Troy Sandberg, Par-Ola Bendahl, Markus Ringner, Per Guldberg, Ake Borg;
Genomic profiling of malignant melanoma using tiling-resolution arrayCGH.
Oncogene 26:4738-4748(2007)

PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235; PMCID=PMC2615688
Keiran S.M. Smalley, Rooha Contractor, Thiennga K. Nguyen, Min Xiao, Robin Edwards, Viswanathan Muthusamy, Alastair J. King, Keith Thomas Flaherty, Marcus W. Bosenberg, Meenhard Herlyn, Katherine L. Nathanson;
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res. 68:5743-5752(2008)

PubMed=19340423; DOI=10.1007/s00262-009-0701-z; PMCID=PMC11030131
Rosa Mendez, Natalia Aptsiauri, Ana Del Campo, Isabel Maleno, Teresa Cabrera, Francisco Ruiz-Cabello Osuna, Federico Garrido, Angel Garcia-Lora;
HLA and melanoma: multiple alterations in HLA class I and II expression in human melanoma cell lines from ESTDAB cell bank.
Cancer Immunol. Immunother. 58:1507-1515(2009)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Christina Dahl, Claus Christensen, Goran Jonsson, Anders Lorentzen, Mette Louise Skjodt, Ake Borg, Graham Pawelec, Per Guldberg;
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

Cross-references
Cell line collections (Providers) Coriell; WC00075 - Discontinued
Rockland; WM1361A-01-0001
Cell line databases/resources cancercelllines; CVCL_6788
ESTDAB; ESTDAB-069
CRISP screens repositories BioGRID_ORCS_Cell_line; 1751
Encyclopedic resources Wikidata; Q54994168
Gene expression databases GEO; GSM109025
GEO; GSM156022
GEO; GSM185174
GEO; GSM185175
GEO; GSM185176
GEO; GSM185177
GEO; GSM952593
Polymorphism and mutation databases Cosmic; 686402
Cosmic; 1047649
Cosmic; 1155284
Cosmic; 1155540
Cosmic; 1303063
Cosmic; 1507599
Cosmic; 1669263
Cosmic; 2163799
Cosmic; 2233686
IARC_TP53; 26076
Progenetix; CVCL_6788
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number30