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Cellosaurus AS-E2 (CVCL_6769)

[Text version]
Cell line name AS-E2
Accession CVCL_6769
Resource Identification Initiative To cite this cell line use: AS-E2 (RRID:CVCL_6769)
Comments Population: Japanese.
Characteristics: EPO dependent.
Doubling time: ~49 hours (PubMed=9369430).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Disease Adult pure erythroid leukemia (NCIt: C68693)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Web pages Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=AS-E2
Publications

PubMed=9369430; DOI=10.1038/sj.leu.2400838
Miyazaki Y., Kuriyama K., Higuchi M., Tsushima H., Sohda H., Imai N., Saito M., Kondo T., Tomonaga M.
Establishment and characterization of a new erythropoietin-dependent acute myeloid leukemia cell line, AS-E2.
Leukemia 11:1941-1949(1997)

PubMed=9419420
Tsushima H., Urata Y., Miyazaki Y., Fuchigami K., Kuriyama K., Kondo T., Tomonaga M.
Human erythropoietin receptor increases GATA-2 and Bcl-xL by a protein kinase C-dependent pathway in human erythropoietin-dependent cell line AS-E2.
Cell Growth Differ. 8:1317-1328(1997)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

Cross-references
Cell line collections (Providers) RCB; RCB5257
Encyclopedic resources Wikidata; Q54750585
Polymorphism and mutation databases Cosmic; 787421
Cosmic; 975239
Cosmic; 1012059
Cosmic; 1281306
Cosmic; 2306200
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number16