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Cellosaurus 86-2 (CVCL_6757)

[Text version]
Cell line name 86-2
Accession CVCL_6757
Resource Identification Initiative To cite this cell line use: 86-2 (RRID:CVCL_6757)
Comments Population: Japanese.
Doubling time: 1.5 days (CelloPub=CLPUB00161; PubMed=7817386).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
HLA typing Source: PubMed=9023415
Class I
Disease Lung large cell carcinoma (NCIt: C4450)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 36Y
Category Cancer cell line
STR profile Source(s): RCB; TKG


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Kobayashi S., Okada S., Inaba H., Syoji W., Hasumi T., Sato N., Fujimura S.
Culture and growth characteristics of human non-small cell lung cancer cells.
Kokenshi 42:73-83(1990)

PubMed=7817386; DOI=10.1620/tjem.173.217
Kobayashi S., Okada S., Yoshida H., Hasumi T., Sato N., Inaba H., Nakada T., Fujimura S.
Syalil-SSEA1(SLX) levels in supernatant of cultured human lung carcinoma cell lines.
Tohoku J. Exp. Med. 173:217-229(1994)

PubMed=9023415; DOI=10.1006/cimm.1996.1062
Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Cell. Immunol. 175:101-110(1997)

PubMed=9538136; DOI=10.3892/ijo.12.5.1103
Takaki T., Hiraki A., Uenaka A., Gomi S., Itoh K., Udono H., Shibuya A., Tsuji T., Sekiguchi S., Nakayama E.
Variable expression on lung cancer cell lines of HLA-A2-binding MAGE- 3 peptide recognized by cytotoxic T lymphocytes.
Int. J. Oncol. 12:1103-1109(1998)

PubMed=15746151; DOI=10.1093/hmg/ddi092
Izumi H., Inoue J., Yokoi S., Hosoda H., Shibata T., Sunamori M., Hirohashi S., Inazawa J., Imoto I.
Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers.
Hum. Mol. Genet. 14:997-1007(2005)

PubMed=16105816; DOI=10.1158/0008-5472.CAN-05-0331
Nagai Y., Miyazawa H., Huqun X., Tanaka T., Udagawa K., Kato M., Fukuyama S., Yokote A., Kobayashi K., Kanazawa M., Hagiwara K.
Genetic heterogeneity of the epidermal growth factor receptor in non-small cell lung cancer cell lines revealed by a rapid and sensitive detection system, the peptide nucleic acid-locked nucleic acid PCR clamp.
Cancer Res. 65:7276-7282(2005)

PubMed=22313637; DOI=10.4161/cbt.19238
Takata M., Chikumi H., Miyake N., Adachi K., Kanamori Y., Yamasaki A., Igishi T., Burioka N., Nanba E., Shimizu E.
Lack of AKT activation in lung cancer cells with EGFR mutation is a novel marker of cetuximab sensitivity.
Cancer Biol. Ther. 13:369-378(2012)

Cell line collections (Providers) RCB; RCB2134
TKG; TKG 0181
Cell line databases/resources CLO; CLO_0050053
CGH-DB; 9185-4
Biological sample resources BioSample; SAMN03472011
Encyclopedic resources Wikidata; Q54605348
Polymorphism and mutation databases Cosmic; 946066
Cosmic; 1048223
Cosmic; 1066157
Cosmic; 1656908
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number16