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Cellosaurus 86-2 (CVCL_6757)

[Text version]
Cell line name 86-2
Accession CVCL_6757
Resource Identification Initiative To cite this cell line use: 86-2 (RRID:CVCL_6757)
Comments Population: Japanese.
Doubling time: 1.5 days (CelloPub=CLPUB00161; PubMed=7817386).
Misspelling: 31444; BioSample=SAMN03472011.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
HLA typing Source: PubMed=9023415
Class I
HLA-AA*11:01
HLA-BB*51:01
HLA-CC*04:01,15:02
Disease Lung large cell carcinoma (NCIt: C4450)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 36Y
Category Cancer cell line
STR profile Source(s): RCB=RCB2134; TKG=TKG 0181

Markers:
AmelogeninX,Y
CSF1PO12,13
D5S81811,12
D7S82011
D13S31711
D16S53912
TH016,7
TPOX8,11
vWA18

Run an STR similarity search on this cell line
Publications

CLPUB00161
Shunsuke Kobayashi, Shinichiro Okada, Hirohisa Inaba, Wataru Syoji, Toru Hasumi, Nobuyuki Sato, Shigefumi Fujimura;
Culture and growth characteristics of human non-small cell lung cancer cells.
Kokenshi 42:73-83(1990)

PubMed=7817386; DOI=10.1620/tjem.173.217
Shunsuke Kobayashi, Shinichiro Okada, Hiroyuki Yoshida, Toru Hasumi, Nobuyuki Sato, Hirohisa Inaba, Tasaku Nakada, Shigefumi Fujimura;
Syalil-SSEA1(SLX) levels in supernatant of cultured human lung carcinoma cell lines.
Tohoku J. Exp. Med. 173:217-229(1994)

PubMed=9023415; DOI=10.1006/cimm.1996.1062
Naoko Seki, Tomoaki Hoshino, Megumi Kikuchi, Akihiro Hayashi, Kyogo Itoh;
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Cell. Immunol. 175:101-110(1997)

PubMed=9538136; DOI=10.3892/ijo.12.5.1103
Toshiyuki Takaki, Akio Hiraki, Akiko Uenaka, Shinya Gomi, Kyogo Itoh, Heiichiro Udono, Akira Shibuya, Takao Tsuji, Sadayoshi Sekiguchi, Eiichi Nakayama;
Variable expression on lung cancer cell lines of HLA-A2-binding MAGE-3 peptide recognized by cytotoxic T lymphocytes.
Int. J. Oncol. 12:1103-1109(1998)

PubMed=15746151; DOI=10.1093/hmg/ddi092
Hiroto Izumi, Jun Inoue, Sana Yokoi, Hiroshi Hosoda, Tatsuhiro Shibata, Makoto Sunamori, Setsuo Hirohashi, Johji Inazawa, Issei Imoto;
Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers.
Hum. Mol. Genet. 14:997-1007(2005)

PubMed=16105816; DOI=10.1158/0008-5472.CAN-05-0331
Yoshiaki Nagai, Hitoshi Miyazawa, Huqun No_last_name, Tomoaki Tanaka, Kiyoshi Udagawa, Motoyasu Kato, Shunichiro Fukuyama, Akemi Yokote, Kunihiko Kobayashi, Minoru Kanazawa, Koichi Hagiwara;
Genetic heterogeneity of the epidermal growth factor receptor in non-small cell lung cancer cell lines revealed by a rapid and sensitive detection system, the peptide nucleic acid-locked nucleic acid PCR clamp.
Cancer Res. 65:7276-7282(2005)

PubMed=22313637; DOI=10.4161/cbt.19238
Miyako Takata, Hiroki Chikumi, Naomi Miyake, Kaori Adachi, Yasunobu Kanamori, Akira Yamasaki, Tadashi Igishi, Naoto Burioka, Eiji Nanba, Eiji Shimizu;
Lack of AKT activation in lung cancer cells with EGFR mutation is a novel marker of cetuximab sensitivity.
Cancer Biol. Ther. 13:369-378(2012)

PubMed=38639832; DOI=10.1007/s13577-024-01055-0; PMCID=PMC11194210
Fumio Kasai, Makoto Fukushima, Yohei Miyagi, Yukio Nakamura;
Genetic diversity among the present Japanese population: evidence from genotyping of human cell lines established in Japan.
Hum. Cell 37:944-950(2024)

Cross-references
Cell line collections (Providers) RCB; RCB2134
TKG; TKG 0181
Cell line databases/resources CLO; CLO_0050053
CGH-DB; 9185-4
Biological sample resources BioSample; SAMN03472011
Encyclopedic resources Wikidata; Q54605348
Polymorphism and mutation databases Cosmic; 946066
Cosmic; 1048223
Cosmic; 1066157
Cosmic; 1656908
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number19