Cellosaurus cell line RCSN-3 (CVCL

Cellosaurus RCSN-3 (CVCL_6719)

Cross-references
Cell line name	RCSN-3
Synonyms	RCSN3; RC SN3; RC SN-3
Accession	CVCL_6719
Resource Identification Initiative	To cite this cell line use: RCSN-3 (RRID:CVCL_6719)
Comments	Doubling time: 52 hours (PubMed=11299314). Transformant: Unknown product of UCHT1 (Cellosaurus=CVCL_9W35) conditioned media. Derived from site: In situ; Brain, substantia nigra; UBERON=UBERON_0002038.
Species of origin	Rattus norvegicus (Rat) (NCBI Taxonomy: 10116) Breed/subspecies: Fischer 344; RS=RS_0000215.
Age at sampling	4M
Category	Transformed cell line
Publications	PubMed=11299314; DOI=10.1046/j.1471-4159.2001.00243.x Irmgard Paris, Alexies Dagnino-Subiabre, Katherine Marcelain, Lori B. Bennett, Pablo Caviedes, Raul Caviedes, Claudio Olea Azar, Juan Segura-Aguilar; Copper neurotoxicity is dependent on dopamine-mediated copper uptake and one-electron reduction of aminochrome in a rat substantia nigra neuronal cell line. J. Neurochem. 77:519-529(2001) PubMed=11355881; DOI=10.1006/bbrc.2001.4907 Pedro Martinez-Alvarado, Alexies Dagnino-Subiabre, Irmgard Paris, Diana Metodiewa, Christopher J. Welch, Claudio Olea-Azar, Pablo Caviedes, Raul Caviedes, Juan Segura-Aguilar; Possible role of salsolinol quinone methide in the decrease of RCSN-3 cell survival. Biochem. Biophys. Res. Commun. 283:1069-1076(2001) PubMed=18522901; DOI=10.1007/BF03033505 Irmgard Paris, Jorge Lozano, Sergio Cardenas, Carolina Perez-Pastene, Katherine Saud, Patricio Fuentes Bravo, Pablo Caviedes, Alexies Dagnino-Subiabre, Rita Raisman-Vozari, Takeshi Shimahara, John P. Kostrzewa ...Show all 15 authors... , David Chi, Richard M. Kostrzewa, Raul Caviedes, Juan Segura-Aguilar; Show fewer authors The catecholaminergic RCSN-3 cell line: a model to study dopamine metabolism. Neurotox. Res. 13:221-230(2008) Patent=US8337829 Thomas B. Freeman, Pablo Caviedes, Raul Caviedes; Conditioned medium and proliferated cell lines produced therefrom. Patent number US8337829, 25-Dec-2012
Anatomy/cell type resources	BTO; BTO_0004200
Encyclopedic resources	Wikidata; Q54949528
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Apr-2025
Version number	13